Infectious Complications following Isolated Lung Transplantation

Maurer, J.R.; Tullis, D. Elizabeth; Grossman, Ronald F.; Vellend, Hillar; Winton, Timothy; Patterson, G. Alexander

doi:10.1378/chest.101.4.1056

Cited by 163 publications

(103 citation statements)

References 11 publications

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“…RVI occurred at a median of 144 days posttransplant (range 1-1276 days; mean 246 days). Organisms included rhinovirus (14), adenovirus (10), parainfluenza (10), influenza (3) and RSV (4). Of the RVI, thirty-eight (82.6%) met the criteria for lower respiratory tract infection (LRI) while eight (17.4%) were recovered from the upper respiratory tract (URI).…”

Section: Rvi Episodesmentioning

confidence: 99%

“…Most lung transplant recipients develop an infectious episode and infection accounts for nearly 40% of all posttransplant mortality (1)(2)(3)(4). Respiratory viral infections (RVI) have been reported in 9-66% of evaluated lung transplant recipients in the literature include a rate of 14% in a large retrospective cohort of pediatric lung transplant recipients (5)(6)(7)(8)(9)(10)(11).…”

Section: Introductionmentioning

confidence: 99%

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499: Long-Term Impact of Respiratory Viral Infection after Pediatric Lung Transplantation

Liu

Worley

Mallory

et al. 2008

The Journal of Heart and Lung Transplantation

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Section: Rvi Episodesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

499: Long-Term Impact of Respiratory Viral Infection after Pediatric Lung Transplantation

Liu

Worley

Mallory

et al. 2008

The Journal of Heart and Lung Transplantation

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“…Infection rates among lung transplant recipients appear to be higher than those encountered in other solid organ transplant populations, likely related to the unique exposure of the lung allograft to the external environment and to the greater magnitude of immunosuppression employed [1,2]. In the following sections, the most common aetiological pathogens will be discussed; the reader seeking a more exhaustive discussion of the full spectrum of infections is referred to a recent review [3].…”

Section: Infectious Complicationsmentioning

confidence: 99%

“…Bacterial infections, in the form of purulent bronchitis, bronchiectasis and pneumonia, re-emerge as a late complication among patients who develop bronchiolitis obliterans syndrome (BOS; chronic rejection). Gram-negative pathogens, in particular Pseudomonas aeruginosa, are most frequently isolated in association with both early and late infectious events [1,2].…”

Section: Bacteriamentioning

confidence: 99%

Medical complications of lung transplantation

Kotloff¹,

Ahya²

2004

Eur Respir J

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Many of the medical complications that arise are the direct consequence of the need to administer potent immunosuppressive agents, with their attendant risks of infection, malignancy and drug toxicity.This article will review the major medical complications, excluding allograft rejection, which may be encountered in the lung transplant recipient. Familiarity with, and vigilance for, these problems should facilitate earlier recognition, more expeditious intervention and more favourable outcomes. Eur Respir J 2004; 23: 334-342. Pulmonary, Allergy, and Critical Care Division,

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“…O uso de ganciclovir profilático e, provavelmente, o emprego de imunoglobulina hiperimune para CMV podem retardar o início e diminuir a severidade da infecção por CMV 26 .…”

Section: Complicaçõesunclassified

Transplante pulmonar na infância

Camargo¹

2002

J. Pediatr. (Rio J.)

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Objective: this article presents a review of the main aspects related to lung transplant in children and shows the experience of the first medical team to perform this procedure in Latin America.Sources: literature review of scientific articles, using the Medline and Lilacs databases.Summary of the findings: the article was organized into topics. Similarities and differences regarding lung transplant in adults were identified. Specific problems presented by children subjected to transplant are discussed, and special emphasis is given to a specific situation: lung transplant with living related donors.Conclusions: advances in adult lung transplant for the treatment of parenchymatous or vascular lung diseases have been successfully employed in the pediatric population during the last few years.J Pediatr (Rio J) 2002; 78 (Supl.2): S113-S122: lung transplant, infancy, indications and results. ResumoObjetivo: este artigo faz uma revisão dos principais aspectos relacionados com o transplante pulmonar na população pediátrica, e traz a experiência da equipe pioneira na realização do procedimento na América Latina. Fontes de dados:foram utilizadas informações através de revisão bibliográfica, realizada por busca direta de artigos científi-cos e por pesquisa nas bases de dados Medline e Lilacs. Síntese dos dados:o artigo é estruturado em tópicos, nos quais procura identificar as semelhanças e as diferenças com o transplante pulmonar do adulto. Discute os problemas específicos da criança transplantada e enfatiza uma situação específica, a do transplante pulmonar com doadores vivos aparentados.Conclusões: os avanços observados no transplante pulmonar realizado em adultos, para tratamento de doenças pulmonares, parenquimatosas ou vasculares, têm sido transferidos, nos últimos anos, para a população pediátrica, com sucesso crescente.J Pediatr (Rio J) 2002; 78 (Supl.2): S113-S122: transplante de pulmão, infância, indicações e resultados. Transplante pulmonar na infância Lung transplant in childrenJosé J. Camargo*, Grupo de Transplante Pulmonar da Santa Casa de Porto Alegre, RS, Brasil IntroduçãoOs primeiros transplantes pulmonares para tratamento de crianças com doenças do parênquima pulmonar, ou de sua vasculatura foram, na realidade, transplantes cardiopulmonares, seguindo uma idéia vigente no início da década de 80, que considerava o transplante cardiopulmonar mais adequado para tratar pacientes com doenças pulmonares terminais, que tinham, ou deviam ter, algum comprometimento cardíaco associado.Com o desenvolvimento da técnica de transplante pulmonar unilateral e bilateral, indubitavelmente mais simples, e a demonstração de que as alterações cardíacas decorrentes de hipertensão pulmonar regrediam com a substituição dos pulmões doentes, o transplante cardiopulmonar se tornou menos freqüente, indicado apenas naqueles casos de hipertensão pulmonar associados a defeitos cardíacos incorrigíveis cirurgicamente, e, esporadicamente, nos casos de doença vascular pulmonar com insuficiên-cia ventricular esquerda (usualmente c...

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Infectious Complications following Isolated Lung Transplantation

Cited by 163 publications

References 11 publications

499: Long-Term Impact of Respiratory Viral Infection after Pediatric Lung Transplantation

499: Long-Term Impact of Respiratory Viral Infection after Pediatric Lung Transplantation

Medical complications of lung transplantation

Transplante pulmonar na infância

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