Infectious Bronchitis Virus in Poultry: Molecular Epidemiology and Factors Leading to the Emergence and Reemergence of Novel Strains of Infectious Bronchitis Virus

Ennaji, Youssef; Khataby, Khadija; Ennaji, Moulay Mustapha

doi:10.1016/b978-0-12-814966-9.00003-2

Cited by 12 publications

(13 citation statements)

References 73 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Contrasting our results with those of Mondal et al ( 70 ), it is interesting to notice how North Carolina samples from the 1960s are more similar to the sequences found in other states than to the samples sequenced for this study, showing quantitatively IBV genetic variation over time. This variation may be explained by the high accumulation of mutations and recombination events in its viral genome that triggers the emergence of distinct IBV variants ( 74 , 95 , 96 ); however, more studies are needed before better inferences are made.…”

Section: Discussionmentioning

confidence: 99%

Development of a Dissemination Platform for Spatiotemporal and Phylogenetic Analysis of Avian Infectious Bronchitis Virus

et al. 2021

View full text Add to dashboard Cite

Infecting large portions of the global poultry populations, the avian infectious bronchitis virus (IBV) remains a major economic burden in North America. With more than 30 serotypes globally distributed, Arkansas, Connecticut, Delaware, Georgia, and Massachusetts are among the most predominant serotypes in the United States. Even though vaccination is widely used, the high mutation rate exhibited by IBV is continuously triggering the emergence of new viral strains and hindering control and prevention measures. For that reason, targeted strategies based on constantly updated information on the IBV circulation are necessary. Here, we sampled IBV-infected farms from one US state and collected and analyzed 65 genetic sequences coming from three different lineages along with the immunization information of each sampled farm. Phylodynamic analyses showed that IBV dispersal velocity was 12.3 km/year. The majority of IBV infections appeared to have derived from the introduction of the Arkansas DPI serotype, and the Arkansas DPI and Georgia 13 were the predominant serotypes. When analyzed against IBV sequences collected across the United States and deposited in the GenBank database, the most likely viral origin of our sequences was from the states of Alabama, Georgia, and Delaware. Information about vaccination showed that the MILDVAC-MASS+ARK vaccine was applied on 26% of the farms. Using a publicly accessible open-source tool for real-time interactive tracking of pathogen spread and evolution, we analyzed the spatiotemporal spread of IBV and developed an online reporting dashboard. Overall, our work demonstrates how the combination of genetic and spatial information could be used to track the spread and evolution of poultry diseases, providing timely information to the industry. Our results could allow producers and veterinarians to monitor in near-real time the current IBV strain circulating, making it more informative, for example, in vaccination-related decisions.

show abstract

Section: Discussionmentioning

confidence: 99%

Development of a Dissemination Platform for Spatiotemporal and Phylogenetic Analysis of Avian Infectious Bronchitis Virus

et al. 2021

View full text Add to dashboard Cite

show abstract

“…51 Because there are many Coronavirus serotypes in poultry. 52 Therefore, protection against bronchitis is provided by the combination of vaccines containing 2 different strains. 53 The COVID-19 vaccine has a single serotype, but it mutates over time.…”

Section: Discussionmentioning

confidence: 99%

How Close are We to a COVID-19 Vaccine?

Özkan¹

2020

J. Pure Appl. Microbiol.

View full text Add to dashboard Cite

This review provides an overview regarding the main aspects of candidate COVID-19 vaccines and pathophysiology of disease. The types of biotechnological candidate vaccines to be developed against COVID-19, their degree of protection and the pathophysiological mechanism of the disease were analyzed in this review article. The literature data on which cruxes for the development of biotechnological candidate vaccines to be wended are based was researched. Data that could give reference to various biotechnological candidate vaccines were reviewed. For this purpose, up-to-date literature data was utilized. The ways to succeed in the development of a vaccine requiring a technological infrastructure are to synthesize the data obtained from long term trials and to put them into practice subsequently. The vaccines to be developed by means of recombinant DNA technology will be a source of inspiration to people for further studies. After a rapid process of vaccine development, the use of COVID-19 vaccine can be mainstreamed among people to prevent the disease. As a result of these practices, the evaluation of which vaccine will be more safe, reliable and effective will be performed after phase studies.

show abstract

“…The major IBV serotypes are characterized in Massachusetts in the USA, 4/91 (793B or CR88) in the UK, D274 (D207, D212, or D1466, D3896, and D3128) in Europe, QX-like reported in China, H120 strain in the Netherlands with several variants introducing local and regional region by transmissions [ 10 , 11 ]. Different types of serotype or genotype of IBV failed to cross-protection against multiple genotypes due to continuous evolution of IBV [ 12 , 13 , 14 , 15 ]. Immunization with multiple serotype vaccines can be given 90% protection against different types of IBV infection instead of homologous vaccines (i.e., “protectotype concept”) [ 16 , 17 , 18 ].…”

Section: Introductionmentioning

confidence: 99%

Factor Influences for Diagnosis and Vaccination of Avian Infectious Bronchitis Virus (Gammacoronavirus) in Chickens

Bhuiyan

Amin

Bakar

et al. 2021

Veterinary Sciences

View full text Add to dashboard Cite

Infectious bronchitis virus (IBV) is a major economic problem in commercial chicken farms with acute multiple-system infection, especially in respiratory and urogenital systems. A live-attenuated and killed vaccine is currently immunized to control IBV infection; however, repeated outbreaks occur in both unvaccinated and vaccinated birds due to the choice of inadequate vaccine candidates and continuous emergence of novel infectious bronchitis (IB) variants and failure of vaccination. However, similar clinical signs were shown in different respiratory diseases that are essential to improving the diagnostic assay to detect IBV infections. Various risk factors involved in the failure of IB vaccination, such as various routes of application of vaccination, the interval between vaccinations, and challenge with various possible immunosuppression of birds are reviewed. The review article also highlights and updates factors affecting the diagnosis of IBV disease in the poultry industry with differential diagnosis to find the nature of infections compared with non-IBV diseases. Therefore, it is essential to monitor the common reasons for failed IBV vaccinations with preventive action, and proper diagnostic facilities for identifying the infective stage, leading to earlier control and reduced economic losses from IBV disease.

show abstract

Infectious Bronchitis Virus in Poultry: Molecular Epidemiology and Factors Leading to the Emergence and Reemergence of Novel Strains of Infectious Bronchitis Virus

Cited by 12 publications

References 73 publications

Development of a Dissemination Platform for Spatiotemporal and Phylogenetic Analysis of Avian Infectious Bronchitis Virus

Development of a Dissemination Platform for Spatiotemporal and Phylogenetic Analysis of Avian Infectious Bronchitis Virus

How Close are We to a COVID-19 Vaccine?

Factor Influences for Diagnosis and Vaccination of Avian Infectious Bronchitis Virus (Gammacoronavirus) in Chickens

Contact Info

Product

Resources

About