Infectious Bronchitis

Roberts, Juliet R.; Chousalkar, Kapil K.

doi:10.1016/b978-0-12-800879-9.00052-4

Cited by 1 publication

(1 citation statement)

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“…The virus primarily replicates in the trachea and causes ciliary stasis, leading to secondary bacterial infection, such as Escherichia coli and Mycoplasma gallisepticum infection [4]. This results in respiratory distress and poor growth performance [5]. In addition, the disease can cause significant loss due to a drop in egg production and poor egg quality [6,7].…”

Section: Introductionmentioning

confidence: 99%

Comparison of Immune-Related Gene Expression in Two Chicken Breeds Following Infectious Bronchitis Virus Vaccination

Chuwatthanakhajorn,

Chang,

Ganapathy

et al. 2023

Animals

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This study aims to identify the immune-related genes and the corresponding biological pathways following infectious bronchitis virus vaccination in Taiwan Country and White Leghorn chicken breeds. Transcriptomic analyses of the spleen of these two breeds were conducted by next-generation sequencing. Compared to White Leghorn chicken, Taiwan Country chicken showed a significantly higher level of anti-infectious bronchitis virus (IBV) antibodies at 14 and 21 days pos vaccination. At 7 days post vaccination, in the Taiwan Country chicken, higher expression of mitogen-activated protein kinase 10, Major histocompatibility complex class 1, and V-set pre-B cell surrogate light chain 3 were found. In contrast, the White Leghorn chicken had a high expression of interleukin 4 induced 1, interleukin 6, and interleukin 22 receptor subunit alpha 2. These findings have highlighted the variations in immune induction between chickens with distinct genetic background and provided biological pathways and specific genes involved in immune responses against live attenuated IBV vaccine.

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