Infections in Total Hip and Total Knee Arthroplasty: Development of a Score To Assess Endogenous Risk of Surgical Site Infections

Debreuve‐Theresette, Adeline; Diallo, S.; Ohl, Xavier; Dehoux, E.; Bajolet, Odile

doi:10.1089/sur.2014.155

Cited by 10 publications

(11 citation statements)

References 18 publications

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“…Nevertheless, the incidence of PJI and the micro-organisms that were isolated were similar to those found in other studies 1,4,34,35 . Finally, although we could adjust for a number of known risk factors through linkage with other registers, there were a number of risk factors not recorded in the registers; e.g., weight/body mass index 36 , smoking 37 , and alcohol consumption 38 . These variables represent individual risk factors and they are only accounted for if the comorbidity is implemented in the Charlson comorbidity index.…”

Section: Discussionmentioning

confidence: 99%

One-year incidence of prosthetic joint infection in total hip arthroplasty: a cohort study with linkage of the Danish Hip Arthroplasty Register and Danish Microbiology Databases

Gundtoft

Pedersen

Schønheyder

et al. 2017

Osteoarthritis and Cartilage

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Section: Discussionmentioning

confidence: 99%

One-year incidence of prosthetic joint infection in total hip arthroplasty: a cohort study with linkage of the Danish Hip Arthroplasty Register and Danish Microbiology Databases

Gundtoft

Pedersen

Schønheyder

et al. 2017

Osteoarthritis and Cartilage

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“…Many of these factors are patient and perioperative related. [3][4][5][6][7][8] However, there remain numerous potentially modifiable risk factors such as the anesthesia technique (eg, neuraxial vs general anesthesia) that may reduce rates of both infectious and noninfectious complications. [9][10][11] The role of neuraxial anesthesia in reducing the SSI after KA or HA is uncertain.…”

mentioning

confidence: 99%

The Impact of Neuraxial Versus General Anesthesia on the Incidence of Postoperative Surgical Site Infections Following Knee or Hip Arthroplasty

Zorrilla-Vaca

Grant

Mathur

et al. 2016

Regional Anesthesia and Pain Medicine

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“…Patient demographics also have been shown to have an impact upon risk of PJI, including age[16], rural residence[16], race[20], male gender[14,18,20,31], and alcohol[26] or tobacco use[23,29,31,32]. Previous operations to the joint (excluding revisions arthroplasty as this was excluded from analysis) increased the risk of PJI[5,32].…”

Section: Resultsmentioning

confidence: 99%

“…Previous operations to the joint (excluding revisions arthroplasty as this was excluded from analysis) increased the risk of PJI[5,32]. …”

Section: Resultsmentioning

confidence: 99%

Predicting lower limb periprosthetic joint infections: A review of risk factors and their classification

George

Drago

Scarponi

et al. 2017

WJO

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AIMTo undertook a systematic review to determine factors that increase a patient’s risk of developing lower limb periprosthetic joint infections (PJI).METHODSThis systematic review included full-text studies that reviewed risk factors of developing either a hip or knee PJI following a primary arthroplasty published from January 1998 to November 2016. A variety of keywords were used to identify studies through international databases referencing hip arthroplasty, knee arthroplasty, infection, and risk factors. Studies were only included if they included greater than 20 patients in their study cohort, and there was clear documentation of the statistical parameter used; specifically P-value, hazard ratio, relative risk, or/and odds ratio (OR). Furthermore a quality assessment criteria for the individual studies was undertaken to evaluate the presence of record and reporting bias.RESULTSTwenty-seven original studies reviewing risk factors relating to primary total hip and knee arthroplasty infections were included. Four studies (14.8%) reviewed PJI of the hip, 3 (11.21%) of the knee, and 20 (74.1%) reviewed both joints. Nineteen studies (70.4%) were retrospective and 8 (29.6%) prospective. Record bias was identified in the majority of studies (66.7%). The definition of PJI varied amongst the studies but there was a general consensus to define infection by previously validated methods. The most significant risks were the use of preoperative high dose steroids (OR = 21.0, 95%CI: 3.5-127.2, P < 0.001), a BMI above 50 (OR = 18.3, P < 0.001), tobacco use (OR = 12.76, 95%CI: 2.47-66.16, P = 0.017), body mass index below 20 (OR = 6.00, 95%CI: 1.2-30.9, P = 0.033), diabetes (OR = 5.47, 95%CI: 1.77-16.97, P = 0.003), and coronary artery disease (OR = 5.10, 95%CI: 1.3-19.8, P = 0.017).CONCLUSIONWe have highlighted the need for the provider to optimise modifiable risk factors, and develop strategies to limit the impact of non-modifiable factors.

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Infections in Total Hip and Total Knee Arthroplasty: Development of a Score To Assess Endogenous Risk of Surgical Site Infections

Abstract: Endogenous infection risk score studied here was found to be relevant in discriminating cases from control groups, but requires validation in a larger cohort.

Cited by 10 publications

References 18 publications

One-year incidence of prosthetic joint infection in total hip arthroplasty: a cohort study with linkage of the Danish Hip Arthroplasty Register and Danish Microbiology Databases

One-year incidence of prosthetic joint infection in total hip arthroplasty: a cohort study with linkage of the Danish Hip Arthroplasty Register and Danish Microbiology Databases

The Impact of Neuraxial Versus General Anesthesia on the Incidence of Postoperative Surgical Site Infections Following Knee or Hip Arthroplasty

Predicting lower limb periprosthetic joint infections: A review of risk factors and their classification

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