Infections in critically ill burn patients

Hidalgo, F.; Mas, D.; Rubio, Mariano Gómez; García-Hierro, P.

doi:10.1016/j.medin.2016.02.001

Cited by 34 publications

(19 citation statements)

References 35 publications

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“…The most common cause of mortality is the infection although systemic inflammatory response syndrome and sepsis are other causes. 12 , 13 In studies carried out by Elsous et al and Li et al burns were responsible for mortality in four and six patients, respectively. 6 , 7 In our case series, no mortality was observed in any of our patients, despite the fact that 62% of our cases were in the severe burn group.…”

Section: Discussionmentioning

confidence: 94%

“… 10 , 14 , 15 The most commonly used antiseptic ointment for burn treatment is silver sulfadiazine although this creates a pseudo-epithelium on the wound. 12 In our clinic, silver sulfadiazine and nitrofurazone ointment are combined in the second dressing, with only silver sulfadiazine used in the first dressing, given that it contains a local anesthetic agent (lidocaine). This scab created by silver sulfadiazine is debrided.…”

Section: Discussionmentioning

confidence: 99%

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Treatment algorithm in 960 pediatric burn cases: A review of etiology and epidemiology

Avcı¹,

Koçak²

2018

Pak J Med Sci

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Objective:Burn injuries are one of the most significant threats to life in both undeveloped and developing countries. In this study, we evaluate the demographic characteristics and treatment methods in pediatric burn cases admitted to our clinic.Methods:A total of 960 patients aged 0–16 years old who were referred to our center with burn injuries between 2015 and 2016 were analyzed in terms of sex, age, etiology, epidemiology, burn percentage, the degree of burn, hospitalization duration, morbidity-mortality, and treatment methods.Results:In the present study, 512 male and 448 female patients were included. Burns were seen mostly among the patients aged 2–4, and the majority of them were extremity burns. The mean hospitalization duration was 10±6.7 days, and the most common source of burn injury was from hot liquids.Conclusion:Burn injuries are a pediatric emergency that needs to be emphasized to reduce occurrences due to the long hospitalization period, the unfavorable mortality and morbidity rates, and increased treatment costs. It is possible to obtain more positive results by way of a standard and easily applicable treatment algorithm in cases of burn injury.

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

Treatment algorithm in 960 pediatric burn cases: A review of etiology and epidemiology

Avcı¹,

Koçak²

2018

Pak J Med Sci

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“…In treatment, silver sulfadiazine cream, bacitracin, and neomycin sulfate pomade were used daily as topical agents convenient with literature. 7 Furthermore, the second degree burn areas were dressed with Aquacell ® and Acticoat ® (Smith and Nephew Plc, London, UK), which were not needed to be changed daily.…”

mentioning

confidence: 99%

Retrospective analysis of patients with burn injury treated in a burn center in Turkey during the Syrian civil war

Yüce

Acar

Erkal

et al. 2017

SMJ

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Objectives:To report the management of burn injuries that occured in the Syria civil war, which were referred to our burn center.Methods:Forty-three patients with burns, injured in the civil war in Syria and whom were referred to Dr. Lütfi Kırdar Kartal Educating and Training Hospital Burn Centre of İstanbul, Turkey between 2011-2015 were analyzed in a retrospective study.Results:Most of our patients were in major burn classification (93%; 40/43) and most of them had burns >15% total on body surface area. Most of them were admitted to our center late after first management at centers with improper conditions and in cultures of these patients unusual and resistant strains specific to the battlefield were produced.Conclusion:Immediate transfer of the patients from the scene of incidence to burn centers ensures early treatment, this factor may be effective on the outcome of these patients.

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“…(1) These patients undergo immunosuppression resulting from burn injury, predisposing them to infection. (2) Furthermore, a major cause of death in burn patients after 24 hours of injury is multiple organ dysfunction syndrome (MODS), a defining characteristic of septic shock.…”

Section: Introductionmentioning

confidence: 99%

“…However, burn-injured patients are commonly misclassified as septic because they commonly manifest the systemic inflammatory response syndrome (SIRS) response after their injury, which is not attributable to sepsis. (1, 6)…”

Section: Introductionmentioning

confidence: 99%

Comparison of Automated Methods Versus the American Burn Association Sepsis Definition to Identify Sepsis and Sepsis With Organ Dysfunction/Septic Shock in Burn-Injured Adults

Rech

Mosier

Zelisko

et al. 2017

Journal of Burn Care & Research

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Objective To develop an algorithm to identify sepsis and sepsis with organ dysfunction/septic shock in burn-injured patients incorporating criteria from the American Burn Association sepsis definition that possesses good test characteristics compared to ICD-9 codes and an algorithm previously validated in non-burn injured septic patients (Martin et al method). Methods This was a retrospective cohort study of consecutive patients admitted to the burn intensive care unit between January 2008 and March 2015. Results Of the 4761 admitted, 8.6% (n=407) met inclusion criteria, of which the case rate for sepsis was 34.2% (n=139; n=48 sepsis; n=91 sepsis with organ dysfunction/septic shock). For sepsis identification, the novel algorithm had an accuracy of 86.0% (95% CI 82.2% – 89.2%), sensitivity of 66.9% (95% CI 59.1% – 74.7%) and specificity of 95.9% (95% CI 93.5% – 98.3%). The novel algorithm had better discrimination (0.81, 95% CI 0.77–0.86) than the ICD-9 method (0.77, 95% CI 0.73–0.81) although this was not significant (p=0.08). For sepsis with organ dysfunction/septic shock, the novel algorithm plus vasopressors (0.67, 95%CI 0.63–0.72) and the ICD-9 method (0.63, 95%CI 0.58–0.68) performed equivocal (p=0.15) but the Martin method (0.76, 95% CI 0.71–0.81) had superior discrimination than other methods (p<0.01). Conclusions The novel algorithm is an accurate and simple tool to identify sepsis in the burn cohort with good sensitivity and specificity and equivocal discriminative ability to ICD-9 coding. The Martin method had superior discriminative ability for identifying sepsis with organ dysfunction/septic shock in burn-injured patients than either the novel algorithm plus vasopressors or ICD-9 coding.

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Infections in critically ill burn patients

Cited by 34 publications

References 35 publications

Treatment algorithm in 960 pediatric burn cases: A review of etiology and epidemiology

Treatment algorithm in 960 pediatric burn cases: A review of etiology and epidemiology

Retrospective analysis of patients with burn injury treated in a burn center in Turkey during the Syrian civil war

Comparison of Automated Methods Versus the American Burn Association Sepsis Definition to Identify Sepsis and Sepsis With Organ Dysfunction/Septic Shock in Burn-Injured Adults

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