Infections in children following renal transplantation

Meseguer, C. García; Martinez, M.; Alonso, A.; Mur, O; Navarro, Mercedes

doi:10.1016/s0041-1345(99)00370-x

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Only a few studies have described the infectious complications of renal transplantation in children, and none has addressed the specific setting of hospitalization due to fever. Owing to the sparsity of data, there are no clear guidelines for risk‐assessment and management of fever in children after solid organ transplantation, such as those available for children with chemotherapy‐induced neutropenia and other immunocompromised pediatric populations .…”

Section: Introductionmentioning

confidence: 99%

Children after renal transplantation hospitalized for fever: Is empirical antibiotic treatment always justified?

Ashkenazi‐Hoffnung

Davidovits

Bilavsky

et al. 2017

Pediatric Transplantation

View full text Add to dashboard Cite

Infections are a major cause of morbidity and mortality after renal transplantation. However, data focusing on children are scarce. The objective of this study was to investigate the frequency and predictors of bacterial infection in pediatric renal transplant recipients in a specific setting of hospitalization due to fever. Clinical and laboratory data were retrospectively collected for all pediatric renal transplant recipients hospitalized for fever in a national renal transplantation center from 2004 to 2012. One hundred and sixty-eight hospital admissions for fever of 52 children were analyzed. A bacterial etiology was diagnosed in 85 admissions (50.6%); 49 cases (57.6%) were documented microbiologically and 36 (42.4%) clinically. Risk factors and markers of bacterial infection included older age, presence of a central venous catheter, sonographic findings, and elevated inflammatory indices. C-reactive protein level was a more sensitive marker than white blood cell count and absolute neutrophil count. In patients without identified risk factors, no bacterial infections were diagnosed. Pediatric renal transplant recipients hospitalized for fever are at high risk of bacterial infections and usually require empirical antibiotic treatment at admission. However, there is a minority of low-risk patients in whom clinicians may consider withholding antibiotic treatment with close follow-up.

show abstract

Section: Introductionmentioning

confidence: 99%

Children after renal transplantation hospitalized for fever: Is empirical antibiotic treatment always justified?

Ashkenazi‐Hoffnung

Davidovits

Bilavsky

et al. 2017

Pediatric Transplantation

View full text Add to dashboard Cite

show abstract

Untitled

2016

Exp Clin Transplant

View full text Add to dashboard Cite

Objectives: Peritoneal dialysis, the preferred long-term renal replacement modality in the pediatric population, can also be used during the post transplant period. Although it is well known that peritonitis or other complications may occur related to the peritoneal dialysis catheter, less is known about complications related to the peritoneal dialysis during the posttransplant period. Our objective was to evaluate the complications related to use of a peritoneal dialysis catheter during the posttransplant period and to determine the optimum time for removal of the peritoneal dialysis catheter. Material and Methods: We retrospectively analyzed 33 chronic peritoneal dialysis patients. Pretransplant and posttransplant demographics and clinical and laboratory data for each patient were recorded, including incidence of peritonitis and incidence of peritoneal dialysis catheter requirement after transplant. Results: Mean age of patients at transplant was 12.8 ± 4.0 years (range, 3.5-18.0 y). Mean catheter removal time was 81.1 ± 36.2 days (range, 22.0-152.0 d). The peritoneal dialysis catheter was used in 6 of 33 patients (18.2%); none of these patients developed peritonitis. In contrast, 2 of the 27 patients who did not use the peritoneal dialysis catheter developed peritonitis. Our data suggest that the need for catheter use occurs predominantly during the first month, and infectious complications usually happen later. Conclusions: Previously, the trend was to not remove the peritoneal dialysis catheter at the time of transplant. However, in light of recent literature and our present study, we recommend that the time of catheter removal should be modified and decided for each patient on an individual basis.

show abstract

Infections in children following renal transplantation

Cited by 2 publications

References 0 publications

Children after renal transplantation hospitalized for fever: Is empirical antibiotic treatment always justified?

Children after renal transplantation hospitalized for fever: Is empirical antibiotic treatment always justified?

Untitled

Contact Info

Product

Resources

About