Infections Due to Lancefield Group C Streptococci

β-Lactam Failure in Treatment of Two Group G Streptococcus dysgalactiae subsp. equisimilis Pharyngitis Patients

“…Patients with groups A, C and G tonsillopharyngitis are usually treated with 10 days of oral amoxicillin (adults, 1,000 mg every 12 h; children, 50 mg/kg/day in two or three divided doses) or clarithromycin (adults, 500 mg every 12 h for at least 10 days; children, 15 mg/kg/day in two divided doses) as an alternative for patients allergic to penicillin (29,30,33). S. pyogenes has been known to penetrate into pharyngeal cells (24), and this may result in penicillin failure (27,32).…”

Streptococcus equi subsp. zooepidemicus meningitis in Peru

“…zooepidemicus is an uncommon human pathogen that belongs to the Lancefield group C streptococci. This organism most often causes respiratory and various secondary infections in horses, mastitis in cows, lymphadenitis in guinea pigs and jaw abscesses in swine (Salata et al, 1989). Group C streptococci also include S. equi subsp.…”

“…Group C streptococci have been reported to cause central nervous system infection, including meningitis, brain abscess and subdural empyema (Salata et al, 1989), most often in people over 70 years of age or neonates, and the condition is rarely reported in young adults (Jovanović et al, 2008). The majority of reported cases are from the UK, Europe and North America (Eyre et al, 2010).…”

In Vitro Activities of Linezolid, Meropenem, and Quinupristin-Dalfopristin against Group C and G Streptococci, Including Vancomycin-Tolerant Isolates

“…Meropenem, linezolid, quinupristin-dalfopristin, vancomycin, and penicillin MICs at which 90% of the isolates were inhibited were 0.06, 2.0, 0.25, 0.5, and <0.016 g/ml, respectively. Meropenem, linezolid, quinupristindalfopristin, and penicillin were active against group C and G streptococci, including vancomycin-resistant strains.There is increasing interest in the role of Lancefield group C streptococci (GCS) and group G streptococci (GGS) as emerging nosocomial and opportunistic pathogens (18,20). The spectrum of human infection caused by these organisms includes primary and secondary bacteremia in healthy and immunocompromised hosts as well as cellulitis, endocarditis, skin and wound infections, meningitis, arthritis, osteomyelitis, pneumonia, abscesses, puerperal infections, and pharyngitis (2,4,6,18,20).…”

“…The spectrum of human infection caused by these organisms includes primary and secondary bacteremia in healthy and immunocompromised hosts as well as cellulitis, endocarditis, skin and wound infections, meningitis, arthritis, osteomyelitis, pneumonia, abscesses, puerperal infections, and pharyngitis (2,4,6,18,20).…”