Infections and antibiotic resistance in nursing homes

Nicolle, Lindsay E.; Strausbaugh, Larry J.; Garibaldi, Richard A.

doi:10.1128/cmr.9.1.1

Cited by 286 publications

(67 citation statements)

References 214 publications

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“…However, E. coli isolated in this patient population showed higher susceptibility percentages for amoxicillin, cotrimoxazole, norfloxacin and nitrofurantoin compared with uropathogenic E. coli isolated from residents of two nursing homes in the south of The Netherlands [12]. The differences in antibiotic susceptibility between the isolates from GP patients and nursing home residents is very likely due to the presence of additional risk factors for the development of antibiotic resistance in the latter population, including antibiotic use, crowding, underlying pathology and the presence of invasive devices [12,18].…”

Section: Discussionmentioning

confidence: 96%

Antibiotic treatment and resistance of unselected uropathogens in the elderly

Nys

Merode

Bartelds

et al. 2006

International Journal of Antimicrobial Agents

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A population-based study was conducted among women over the age of 70 years with complaints of uncomplicated urinary tract infections (UTIs). The positive predictive value of the nitrite test alone or in combination with the leukocyte esterase test ranged between 83% and 99%. The nitrofurantoin prescription rate decreased whereas fluoroquinolone and amoxicillin/clavulanic acid prescriptions increased with increasing age. The aetiology of infection was age-dependent. Escherichia coli was the most commonly isolated uropathogen, followed by Proteus mirabilis and Klebsiella pneumoniae. For these uropathogens, the lowest susceptibility percentages were found for amoxicillin, trimethoprim and co-trimoxazole. As trimethoprim susceptibility reached approximately 75%, it may be advisable not to use this as a first-choice agent in the treatment of uncomplicated UTIs in the elderly.

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Section: Discussionmentioning

confidence: 96%

Antibiotic treatment and resistance of unselected uropathogens in the elderly

Nys

Merode

Bartelds

et al. 2006

International Journal of Antimicrobial Agents

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“…Many elderly residents of nursing homes have a wide range of clinical disabilities. Urinary incontinence is common, affecting as many as 50% of residents in some nursing homes [14]. Use of indwelling catheters or other urologic treatment for urinary incontinence probably increases the incidence of UTI.…”

Section: Utis In Long-term Care Facilitiesmentioning

confidence: 99%

Urinary tract infections in the elderly

Matsumoto

2001

Curr Urol Rep

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The elderly population is now increasing in the world. A higher incidence of bacteriuria and urinary tract infection (UTI) is observed in elderly patients, in both long-term care facilities and at home. The management of elderly patients with UTI is increasing in clinical significance. Almost all of UTI in the elderly is complicated UTI. Control of the underlying diseases in the urinary tract is quite important in the management of UTIs in elderly patients. For pyelonephritis, switch therapy using aminoglycosides and fluoroquinolones, carbapenems, third-generation cephalosporines, or penicillins are selections of choice. The recommended duration of treatment for patients with pyelonephritis is 14 days. Seven to 10 days of treatment using fluoroquinolones or trimethoprim-sulfamethoxazole is recommended for the treatment of elderly patients with symptomatic cystitis. Although asymptomatic bacteriuria is quite common in the elderly population, antibiotic treatment has no benefit for such patients. Intravaginal estrogen replacement is one of choice for the prevention of recurrent UTIs in postmenopausal women.

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“…This prompted the development of new policies to improve the quality of care in these facilities. Prevention and management of infections and pressure ulcers were selected by the regional health authority as critical components of efforts to improve the quality of care in long-term care facilities (LTCFs), because of the high prevalence of infections in elderly nursing home residents and the morbidity and costs associated with them, as shown by several studies in the US [4][5][6][7][8][9][10]. This study describes the prevalence of infections and their associated factors in a representative sample of nursing homes in three local health authorities (LHAs) in the Emilia-Romagna region.…”

Section: Introductionmentioning

confidence: 99%