Infection with Ralstonia insidiosa in two patients

Ralstonia insidiosa Neonatal Sepsis: A Case Report and Review of the Literature

“…18 Van der beek et al also reported R. insidiosa to be susceptible to cefotaxime, cefepime, cotrimoxazole, ciprofloxacin, piperacillin-tazobactam, and meropenem and resistant to ampicillin, gentamicin, and amikacin. 4 In our case, the pathogen was resistant to ampicillin, gentamicin, and cefazolin. Antibiotics were changed from ampicillin and gentamicin to ampicillin-sulbactam and cefotaxime in view with these results, leading to clinical and laboratory improvement of the neonate.…”

“…5 Van der beek et al reported two cases, one of which was a catheter-related R. insidiosa infection accompanying bacteremia, and in the other R. insidiosa was reported to be the cause of pneumonia. 4,5 Ryan and Adley reported high resistance to gentamicin and aztreonam, variable resistance to ticarcillin-clavulanic acid for various strains of R. pickettii and R. insidiosa, and that there was little difference in antibiotic resistance between clinical and environmental isolates of the two bacteria. 18 Van der beek et al also reported R. insidiosa to be susceptible to cefotaxime, cefepime, cotrimoxazole, ciprofloxacin, piperacillin-tazobactam, and meropenem and resistant to ampicillin, gentamicin, and amikacin.…”

“…2,3 Previously, two case series of infection associated with R. insidiosa have been published. 4,5 In this case report, R. insidiosa infection of a neonate in the neonatal intensive care unit (NICU) is presented.…”

Bacterial Contamination in Cold Water Samples Obtained from Water Dispensers

“…P. aeruginosa is widely distributed in the natural environment Aoi et al, 2000 , which increases the risk of it contaminating water dispensers. However, this bacterium is a pathogen associated with opportunistic infections Edamoto et al, 2009 , requiring special attention with respect to the potential for healthcare-associated infections Spencker et al, 2000 . Furthermore, Ralstonia pickettii Woo et al, 2002 and R. insidiosa Van der beek et al, 2005 , which exhibited the highest isolation rates observed in this study, also include species that may influence health. These bacteria are widely distributed in the natural world, including in water, soil and plants.…”

“…In other words, it is advisable to consider how to prevent primarily indigenous to the upper respiratory tract, such as the oral cavity, pharynx, trachea, etc. Therefore, while it is very rare for a healthy person to develop an infection caused by these bacteria, those with an immune deficiency or reduced resistance may develop respiratory infections or blood poisoning due to these organisms Woo et al, 2002;Van der beek et al, 2005 . It has also been reported that these bacteria function as pathogens of healthcare-assoc iated infections Ryan et al, 2006 .…”