Infection with COVID-19 promotes the progression of pancreatic cancer through the PI3K-AKT signaling pathway
Xusheng Zhang,
Bendong Chen,
Kejun Liu
et al.
Abstract:Objective
To investigate the effect of COVID-19 infection on pancreatic cancer.
Methods
Based on the mRNA-Seq data of COVID-19 patients and pancreatic cancer (PC) patients in the GEO database, we used a support vector machine (SVM), LASSO-Cox regression analysis and random forest tree (RF) to screen the common signature genes of the two diseases and further investigate their effects and functional characteristics on PC, respectively. The above proc… Show more
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