Infection-Related Ventilator-Associated Complication and Possible Ventilator-Associated Pneumonia among Mechanically Ventilated Patients of Adult Medical and Surgical Intensive Care Units

Abstract

Objective An observational study was conducted to evaluate (1) the incidence rates of infection-related ventilator-associated complication (IVAC) and possible ventilator-associated pneumonia (PVAP) among mechanically ventilated patients of adult medical and surgical intensive care units (ICUs) and (2) the pathogen distribution in patients with PVAP. Materials and Methods The IVAC and PVAP rates of medical and surgical ICUs, between July 1, 2017, and June 30, 2021, per 1,000 mechanical ventilator (MV) days were calculated. The significance of difference in IVAC and PVAP rates between medical and surgical ICUs was calculated. The level of significance was set at less than 0.05. Results MV utilization ratios of adult medical and surgical ICUs were 0.32 and 0.26, respectively (p < 0.001). About 8 and 7 episodes of IVAC and 14 and 6 episodes of PVAP were reported from adult medical and surgical ICUs, accounting for IVAC rates of 3.17 and 1.8 per 1,000 MV (p > 0.05) and PVAP rates of 2.46 and 1.59 per 1,000 MV days in medical and surgical ICUs, respectively (p > 0.05). Acinetobacter baumannii complex either singly or in combination was isolated in 11/20 PVAP cases. Conclusion IVAC and PVAP were more in medical compared with surgical ICUs. The most common pathogen in patients with PVAP was A. baumannii complex. More studies are warranted to monitor the significance of ventilator-associated event on patient outcomes.

Treatment and Management of Acinetobacter Pneumonia: Lessons Learned from Recent World Event

“…71,75,76 The increasing prevalence of VAP caused by MDRAB and CRAB emphasizes the critical need for focused attention on preventative strategies and alternative treatment approaches in the ICU setting. [77][78][79] Research conducted over seven years at a tertiary center in Lebanon, focusing on MDRAB infections, revealed that the respiratory tract was the most frequent site of infection/colonization, with rates of 53.1% and 80.8%, respectively. 80 In a study conducted at a university hospital, the rates of multidrug-resistant A. baumannii (MDRAB), XDR, and pan drug-resistant (PDR) strains recovered from VAP cases were 13.3%, 68.3%, and 18.3%, respectively.…”