Infection-related stress phenomenon induced takotsubo cardiomyopathy mimicking ST elevation myocardial infarction

Sun, Teh-Kuang

doi:10.1016/j.jcgg.2014.10.001

Cited by 3 publications

(4 citation statements)

References 11 publications

(16 reference statements)

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“…Another contributor of TS to be considered is acute infection. 17 Although her SARS-CoV-19 swabs were negative, data have shown that the sensitivity of nasopharyngeal swabs decreases as the disease progresses. 18 The clinical suspicion remained high as she presented with a 4-day history of cough and pyrexia along with classical CT changes which suggest SARS-CoV-19 infection with no other cause being found.…”

Section: Discussionmentioning

confidence: 99%

Case report of Takotsubo syndrome following seizures in a patient with pyruvate carboxylase deficiency

Sahdev

Oji

Babu

et al. 2021

European Heart Journal - Case Reports

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Background Takotsubo syndrome (TS) is defined as transient left ventricular dysfunction, which is often related to an emotional or physically stressful event. We describe a case of TS in a lady with pyruvate carboxylase deficiency (PCD). Pyruvate carboxylase deficiency is rare condition with the majority of those affected demonstrating signs of failure to thrive, recurrent seizures, and metabolic acidosis. To our knowledge, this is the first documented case of TS in an individual with PCD. Case summary This 28-year-old female presented to the emergency department after a tonic-clonic seizure. For 4 days prior to the presentation, she had been suffering from cough and pyrexia. On Day 2, she developed abdominal pain associated with tachycardia and hypotension, and an elevated troponin (791 ng/L). The echocardiogram showed a severely impaired left ventricular systolic function, regional wall motion abnormalities (RWMAs), and a visually estimated left ventricular ejection fraction of 25–30%. Eight days following admission her clinical state significantly improved, with a reduction troponin to 60 ng/L. A repeat echocardiogram on Day 9 showed complete resolution of cardiac function with no RWMAs. Following this, she was discharged from hospital the next day with a diagnosis of TS. Discussion This is the first case report of TS in a patient with PCD. In this case, multiple aetiologies of TS such as emotional and physical stress, seizures, and acute infection were considered. This case also highlights that TS should be an important differential diagnosis in patients presenting with cardiac symptoms.

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Section: Discussionmentioning

confidence: 99%

Case report of Takotsubo syndrome following seizures in a patient with pyruvate carboxylase deficiency

Sahdev

Oji

Babu

et al. 2021

European Heart Journal - Case Reports

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“…Rarely, an infection may be the cause. Severe infection can cause above-mentioned physiological response and theoretically may precipitate TTC in susceptible individuals [8] . In this case, we did not find any emotional stressor.…”

Section: Discussionmentioning

confidence: 99%

A rare manifestation of Takotsubo Cardiomyopathy associated with non-tuberculous mycobacterium

Saboe

Sari

Febrianora

2020

Journal of Clinical Tuberculosis and Other Mycobacterial Diseas

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Background Takotsubo Cardiomyopathy or broken heart syndrome is a rare cause of non-ischemic cardiomyopathy that produce left ventricular dysfunction with characteristic left ventricular apical ballooning. It rarely caused by infection. We present an atypical manifestation of non-tuberculous mycobacterial (NTM) infection with myocardial involvement and its diagnostic challenge. Case illustration A 57-year-old female presented with prolonged fever, fatigue and weight loss for one and half months. General examination was unremarkable with elevated C-Reactive Protein and normal troponin. Electrocardiogram (ECG) showed diffuse T wave inversion with prolonged QTc. Echocardiography showed hypokinetic apical with normal ejection fraction. Angiography showed patent coronary arteries. Ventriculography showed apical ballooning. Workup with ethambutol scan revealed active mycobacterial infection in both lung and mesentery. Sputum polymerase chain reaction (PCR) was positive for non-tuberculous mycobacterium. Follow up ECG and echocardiography showed improvement in QTc interval and left ventricular wall motion abnormalities. Results Takotsubo Cardiomyopathy may manifest as asymptomatic ventricular dysfunction following non-tuberculous mycobacterial infection. A thorough investigation will help identify the systemic disease with cardiac involvement which potentially could be fatal. Conclusion Takotsubo cardiomyopathy may be triggered by infection. Identification of causal is crucial as a management strategy to restore cardiac function.

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“…It is characterized by apical ballooning and transient left ventricular dysfunction, which usually improves within a few days or weeks. Although this condition is most commonly seen in postmenopausal women typically after an emotional stressor, it has also been reported in younger individuals, men, and even children [4,9].…”

Section: Discussionmentioning

confidence: 99%

“…Although the exact mechanism contributing to this condition remains undescribed, catecholamine surge has been shown to have a role in precipitating TTCM [2][3]. Several infections have also been shown to precipitate TTCM; however, there have been very few cases describing its association with liver abscess [4][5][6][7]. We present a rare case of Takotsubo cardiomyopathy precipitated by the liver abscess.…”

Section: Introductionmentioning

confidence: 90%

Broken Heart Syndrome Secondary To Liver Abscess

Nair

Lak

Ahmed

et al. 2020

Cureus

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Infection-related stress phenomenon induced takotsubo cardiomyopathy mimicking ST elevation myocardial infarction

Cited by 3 publications

References 11 publications

Case report of Takotsubo syndrome following seizures in a patient with pyruvate carboxylase deficiency

Case report of Takotsubo syndrome following seizures in a patient with pyruvate carboxylase deficiency

A rare manifestation of Takotsubo Cardiomyopathy associated with non-tuberculous mycobacterium

Broken Heart Syndrome Secondary To Liver Abscess

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