Abstract:Infection with the protozoan Toxoplasma gondii induces changes in neurotransmission, neuroinflammation, and behavior. Yet, it remains elusive how these changes are wrought by the small percentage of neurons that are infected. In this study we investigated how neurotransmission is altered in uninfected neurons during infection by studying suppression of noradrenergic signalling. Noradrenergic signalling is central in modulating the neuroinflammatory response. Previous studies found decreased norepinephrine and … Show more
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