Infection bactérienne à Streptococcus gallolyticus transmise par transfusion d’un concentré de plaquettes : à propos d’un cas

Niger, Catherine Le; Dalbies, F.; Narbonne, V.; Héry-Arnaud, Geneviève; Virmaux, Michèle; Leostic, C.; Hervé, F.; Liétard, Claire

doi:10.1016/j.tracli.2014.05.001

Cited by 2 publications

(1 citation statement)

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“…Later, a colonoscopy revealed a colonic neoplasm, and a biopsy revealed the diagnosis of invasive adenocarcinoma. In 2014, Le Niger et al 13 published an analysis of a case of an 80-year-old female with an asymptomatic rectal tumor that was discovered because of a platelet concentrate infected with S. gallolyticus . In this case, the patient only discovered the tumor because the Hemotherapy Service was aware of the correlation between platelet contamination and CRC and requested further investigation with colonoscopy.…”

Section: Discussionmentioning

confidence: 99%

Streptococcus gallolyticus Bacteremia Detected in Apheresis Platelets and Its Link to Colonic Neoplasms

Lemanski

Barp

Hammacher

et al. 2022

Journal of Coloproctology

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Introduction Streptococcus gallolyticus belongs to the Streptococcus bovis complex, and it is a common bacterium colonizing the gastrointestinal tract. Its presence in the blood may suggest an underlying pathology such as a colonic neoplasm. We report herein a case of S. bovis bacteremia in an apheresis platelet donor, review similar cases in the literature, and suggest a flowchart for the management of similar cases in other blood donation centers. Case Presentation A 61-year-old subject presented to a Hemotherapy Service to make an apheresis platelet donation. On quality control testing, S. gallolyticus was identified in hemoculture, and the donor was called back for follow-up. At first, a new hemoculture was requested, and the patient was referred to the outpatient department of infectious diseases to further investigate pathologies associated with S. gallolyticus. A subsequent colonoscopy investigation evidenced a polypoid structure in the ascending colon. Pathology reported the resected specimen as a low-grade tubular adenoma. Conclusion Isolation of S. bovis in blood products requires further investigation and should be managed with precision by Hemotherapy Services. A standard protocol for the management of asymptomatic patients with S. bovis positive hemoculture, with the requests of a new blood culture, a colonoscopy, and an echocardiogram is crucial, as it may ensure early diagnosis and reduce morbidity and mortality.

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Section: Discussionmentioning

confidence: 99%