Infection and pyospermia in male infertility

Bar‐Chama, Natan; Fisch, Harry

doi:10.1007/bf00182033

Cited by 46 publications

(27 citation statements)

References 53 publications

(54 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Infectious processes can impair fertility by different mechanisms, including deterioration of spermatogenesis, impairment of sperm function, and obstruction of the seminal tract (Bar-Chama and Fisch, 1993;Purvis and Christiansen, 1996).…”

Section: Introductionmentioning

confidence: 99%

Seminal tract infections: impact on male fertility and treatment options

Keck¹,

Gerber-Schäfer²,

Clad³

et al. 1998

Human Reproduction Update

251

189

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Seminal tract infections: impact on male fertility and treatment options

Keck¹,

Gerber-Schäfer²,

Clad³

et al. 1998

Human Reproduction Update

251

189

View full text Add to dashboard Cite

“…Many contemporary studies (7,14,15) concerning the correlation between pyospermia or leucocytospermia and decreased semen parameters. Those authors claim that asymptomatic pyospermia has great influence on male infertility, with significant occurrence, and it can reflect infectious or inflammatory disorders.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Sperm Parameters in Patients with Infertility Induced by Genital Infection versus Varicocele

et al. 2015

View full text Add to dashboard Cite

Background: Male infertility is a common and complex problem and, despite much research in this field, the major cause of infertility unfortunately remains unknown. Genital infection and varicocele are important causes of infertility. Aims: To compare the influence of genital infection and varicocele individually on male infertility based on semen analysis. Study Design: Cross-sectional study. Methods: The study included 120 infertile patients divided into two groups according to the presence of genital infection or varicocele. The first group included 60 examinees with proven genital infection, but without varicocele formation. The second included 60 patients with varicocele, regardless of the varicocele grade, but without genital infection. The fertile parameters were compared and an assessment was performed on the impact on quality of spermatogenesis due to infection and varicocele. Results: There is a statistically significant difference regarding abnormal forms of spermatozoids (45.94±9.79 vs. 25.27±6.54) and progressive motility (8.15±1.24 vs. 24.95±7.2), between two groups of patients. However, acidity of ejaculates, minimum sperm concentration, total spermatozoid motility and ejaculate volume showed no statistically significant difference. Conclusion:The study showed a stronger negative influence of genital infection on fertile parameters over varicocele. The significance of our study is the lack of contemporary researches comparing varicocele and genital infection influence on male infertility individually. Keywords: Genital infections, infertility, semen analysis, varicocele Infertility is related to the disability of a sexually active, couple not using contraception to become pregnant within one year. Male infertility is a complex, contemporary problem, which affects approximately every 20 th person. The etiology of infertility usually remains unknown, despite detailed and comprehensive research in this field (1-3).Genital infection and varicocele are the main causes of male infertility worldwide. Genital infection can impair the quality of spermatozoa and decrease the function of male accessory glands. Nevertheless, it is a correctable cause of male infertility (4). Contemporary studies claim that varicocele can be associated with significant and progressive testicular damage if started during adolescence, which can permanently decrease fertility. Nevertheless, only a small percentage of men with varicocele are infertile, although almost 30% of men with abnormal semen parameters have clinical varicocele (5,6). Initially, the diagnosis of infertility in males is established through the analysis of semen (7).Since there is no contemporary research with regards to the comparison between genital infection and varicocele influence on male infertility, the aim of our research is to compare genital infection and varicocele influence on male infertility, separately, based on semen analysis.

show abstract

“…Traditionally, bacteria such as E. coli or N. gonorrhea were considered to be the main infectious sources. In recent years, however, many other pathogens, such as chlamydia, ureaplasma, and urealyticum, and viruses, such as cytomegalovirus (CMV), herpes simplex virus (HSV), human papilloma virus (HPV), and human immunodeficiency virus type 1 (HIV-l), have been reported to be common STD-related urogenital tract pathogens in both men and women [8]. Infections stimulate inflammatory reactions, which are characterized by infiltration of white blood cells, mainly PMN leukocytes.…”

Section: Discussionmentioning

confidence: 99%