Infection and Inflammation of the Pediatric Genitourinary Tract

Randomized Crossover Trial of Single Use Hydrophilic Coated vs Multiple Use Polyvinylchloride Catheters for Intermittent Catheterization to Determine Incidence of Urinary Infection

“…Moreover, bacteria are likely to grow in this population even in the absence of active infection. 10 In addition, it would have been ideal to collect data for 6 to 12 months on symptomatic UTI as a lead-in to the study, and to have some clear before and after data, as it is well known that subject recall is typically incorrect. However, it was not feasible logistically to extend the study an additional year.…”

Infección urinaria en pediatría

“…Estas son producidas por células epiteliales de la vejiga, uréter, uretra y riñón, así como por los neutrófilos polimorfonucleares (PMNs) y macrófagos. 16,19,22 Dentro de los mecanismos de defensa del tracto urinario están el pH ácido de la orina; el flujo descendente de orina del riñón a la vejiga y su vaciamiento por la uretra; la proteína de Tamm-Horsfall que se adhiere a las fimbrias tipo I de la E. coli participa en la defensa del huésped, evita su fijación, disminuye la lesión e inflamación y posterior desarrollo de infección; la inmunoglobulina A secretora 2,16,19,23 ; y la diseminación hematógena que es más frecuente en los neonatos y lactantes pequeños, en quienes a partir de un cuadro de bacteriemia se produce la infección del parénquima renal. 24 Después de esta edad la vía ascendente es la principal ruta.…”

Diagnostic accuracy of Tc-99m DMSA scintigraphy and renal ultrasonography for detecting renal scarring and relative function in patients with spinal dysraphism

“…However, the evidence base for these recommendations is poor. In pediatric and adolescent literature, the added value of DMSA‐scintigraphy in the follow‐up of patients with SD is widely recognized; renal scarring increases the risk of longer‐term renal failure and hypertension . However, since hard evidence for the value of DMSA‐scintigraphy in adults with SD is lacking, we studied the diagnostic value of DMSA‐scintigraphy with respect to renal scarring, compared with renal ultrasonography, in these patients.…”

“…In pediatric and adolescent literature, the added value of DMSA-scintigraphy in the follow-up of patients with SD is widely recognized [3][4][5][6] ; renal scarring increases the risk of longerterm renal failure and hypertension. 7,8 However, since hard evidence for the value of DMSA-scintigraphy in adults with SD is lacking, we studied the diagnostic value of DMSA-scintigraphy with respect to renal scarring, compared with renal ultrasonography, in these patients. In addition, we investigated whether pole-to-pole kidney length and cortical thickness as measured on ultrasound correlate with split renal function.…”