Infecciones virales respiratorias en una cohorte de niños durante el primer año de vida y su papel en el desarrollo de sibilancias

Calvo, Cristina; Aguado, Isabel; García-García, Maria Luz; Ruiz-Chercoles, Esther; Díaz-Martinez, Eloisa; Albañil, Rosa María; Campelo, Olga; Olivas, Antonio; Muñóz-Gonzalez, Luisa; Pozo, Francisco; Fernandez-Arroyo, Rosa; Fernandez-Rincón, Adelaida; Calderón, Ana Belén Mayo; Casas, Inmaculada

doi:10.1016/j.anpedi.2016.08.002

Cited by 11 publications

(4 citation statements)

References 26 publications

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“…The authors showed that infants who required hospitalization for their first viral infection had an increased risk of developing recurrent wheezing, compared to infants whose first viral infection was mild or asymptomatic. 26 Furthermore, Bønnelykke et al 16 evaluated the association between viral respiratory infections (HRSV, rhinovirus, among others) and bacterial infections in infants, and the development of asthma in childhood. They concluded that the total number of respiratory infections suffered at an early age was a risk factor for developing asthma, regardless of the specific causal agent.…”

Section: Discussionmentioning

confidence: 99%

Recurrent wheezing: prevalence and associated factors in infants from Buenos Aires City, Argentina

Szulman¹,

Freilij²,

Behrends³

et al. 2023

BMHIME

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Background:The episodes of bronchial obstruction at early age constitute a frequent problem in Pediatrics. This study aimed to evaluate the prevalence of recurrent wheezing in infants in Buenos Aires City and to identify its associated factors. Methods: a Cross-sectional study performed from 2011 to 2012 in the Children Hospital Ricardo Gutiérrez, Buenos Aires City, as part of the International Study of Wheezing in Infants. A validated questionnaire was applied to parents of infants aged between 12 and 15 months. The wheezing prevalence, mainly in recurrent patients (three or more episodes) was evaluated, and its likely associated factors. Data were statistically analyzed employing χ 2 test, Fisher's test, binary, and logistics multiple regression analysis, with a significance level of 0.05. Results: Over 1063 infants, 58.9% (confidence interval (CI) 95% 55.9-61.9) had at least one episode of wheezing and 26.3% (CI95% 23.8-29.9) had three or more episodes (recurrent wheezing). Risk factors associated to wheezing were male sex (p = 0.001), six or more episodes of cold during the first year of life (p < 0.0001), age at first cold <4 months (p < 0.0001); pneumonia (p < 0.0001) and tobacco smoking during pregnancy (p = 0.01). For recurrent wheezing, risk factors we considered as six or more episodes of cold during the first year of life (p < 0.0001), early (< 4 month old) onset wheezing (p < 0.0001) and nocturnal wheezing (p < 0.0001). Conclusions: The prevalence of recurrent wheezing among infants in Buenos Aires City was high (26.3%). Some identified associated factors can be preventable.

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Section: Discussionmentioning

confidence: 99%

Recurrent wheezing: prevalence and associated factors in infants from Buenos Aires City, Argentina

Szulman¹,

Freilij²,

Behrends³

et al. 2023

BMHIME

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“…Several severe AB phenotypes have already been identified, and research in this field continues to grow. 36 Thus, some of the current evidence suggests that AB due to rhinovirus has specific clinical and epidemiological characteristics 37 as well as a different long-term prognosis in relation to atopic asthma. 38,39 A viral aetiology is emphasised in descriptions of AB or specifically included in the definitions of disease proposed by some guidelines, 6,9,25---27,34 and many clinical trials only enrol children with infection by RSV.…”

Section: Discussionmentioning

confidence: 99%

Criteria heterogeneity in the diagnosis of acute bronchiolitis in Spain

Cano-Garcinuño¹,

Praena-Crespo

Mora-Gandarillas³

et al. 2019

Anales de Pediatría (English Edition)

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Introduction: Acute viral bronchiolitis (AB) is one of the most common respiratory diseases in infants. However, diagnostic criteria for AB are heterogeneous and not very well known. Objective: To identify the diagnostic criteria for AB used by experts and clinical paediatricians in Spain. Methods: Delphi study with Spanish AB experts, looking for the points of agreement about AB diagnosis. A subsequent cross-sectional study was conducted by means of an online questionnaire addressed to all Spanish paediatricians, reached through electronic mail messages sent by nine paediatric scientific societies. Descriptive and factorial analyses were carried out, looking for any association of diagnostic criteria with demographic or geographic variables, or with paediatric subspecialty. Results: Agreement was reached by 40 experts in many issues (first episode of respiratory distress and high respiratory frequency, diagnosis in any season of the year, and usefulness of virus identification in making diagnosis), but opposite views were maintained on key characteristics

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“…Varios fenotipos de BA grave han sido ya identificados y continúa la investigación en este campo 36 . En este sentido, algunos datos hacen pensar que la BA debida a infección por rinovirus tiene características clínicas y epidemiológicas particulares 37 , y un diferente pronóstico a largo plazo en cuanto a su relación con el asma atópico 38,39 . La etiología vírica se destaca en las descripciones de la enfermedad o se incorpora específicamente en la definición en algunas guías 6,9,25---27,34 , y muchos ensayos clínicos incluyen solo niños con infección por VRS 7 .…”

Section: Discussionunclassified

Heterogeneidad de criterios en el diagnóstico de bronquiolitis aguda en España

Garcinuño¹,

Praena-Crespo

Mora-Gandarillas³

et al. 2019

Anales de Pediatría

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Infecciones virales respiratorias en una cohorte de niños durante el primer año de vida y su papel en el desarrollo de sibilancias

Abstract: In our series, severe respiratory infections leading to hospitalisation in the first months of life are risk factors for developing wheezing, but not in the case of mild RV infections.

Cited by 11 publications

References 26 publications

Recurrent wheezing: prevalence and associated factors in infants from Buenos Aires City, Argentina

Recurrent wheezing: prevalence and associated factors in infants from Buenos Aires City, Argentina

Criteria heterogeneity in the diagnosis of acute bronchiolitis in Spain

Heterogeneidad de criterios en el diagnóstico de bronquiolitis aguda en España

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