Infecciones respiratorias virales en episodios de fiebre en niños con trasplante de precursores hematopoyéticos

Torres, Juan Pablo; Castro-Moraga, María Eugenia; Catalán, Paula; Maza, Verónica De la; Vergara, Alejandra; Valenzuela, Rodrigo; Tapia, Lorena I.; Olivares-Morales, Mauricio; Farfán, Mauricio J.; Santolaya, Marı́a Elena

doi:10.4067/s0716-10182020000400371

Rev. chil. infectol.

2020

DOI: 10.4067/s0716-10182020000400371

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Infecciones respiratorias virales en episodios de fiebre en niños con trasplante de precursores hematopoyéticos

Juan Pablo Torres

María Eugenia Castro-Moraga

Paula Catalán

et al.

Abstract: Los autores declaran no tener conflicto de interés. Proyecto financiado por el Proyecto FONDECYT Regular 1171795 Juan Pablo Torres y María Eugenia Castro-Moraga son ambos primeros co-autores del presente estudio.

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2024

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Respiratory viral infections in children with cancer and febrile neutropenia and children undergoing hematopoietic stem cell transplantation

Torres,

Santolaya

2024

Current Opinion in Infectious Diseases

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Purpose of review The scope of this review is to understand the epidemiology and potential role of respiratory viral infections in children with cancer and febrile neutropenia, as well as in children, undergoing hematopoietic stem cell transplantation. Early detection of respiratory viral infections through molecular diagnostic techniques has allowed recent randomized clinical studies to advance the possibility of more rational use of antimicrobials in this susceptible population. Recent findings Progress has been made in the early detection of respiratory viruses in episodes of fever and neutropenia in children with cancer. In selected patients who meet specific clinical safety criteria and have negative bacterial cultures, it has been possible to safely and effectively discontinue antimicrobials. This has been validated in recent randomized clinical studies. However, more evidence is still needed for a similar indication in children, undergoing hematopoietic stem cell transplantation with viral respiratory infection episodes. Summary Understanding the role of respiratory viral infections in populations of immunocompromised children may contribute to a more rational use of antimicrobials and, in the near future, may help to decrease antimicrobial resistance in this susceptible population.

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Respiratory viral infections in children with cancer and febrile neutropenia and children undergoing hematopoietic stem cell transplantation

Torres,

Santolaya

2024

Current Opinion in Infectious Diseases

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Infecciones respiratorias virales en episodios de fiebre en niños con trasplante de precursores hematopoyéticos

Abstract: Los autores declaran no tener conflicto de interés. Proyecto financiado por el Proyecto FONDECYT Regular 1171795 Juan Pablo Torres y María Eugenia Castro-Moraga son ambos primeros co-autores del presente estudio.

Cited by 1 publication

References 21 publications

Respiratory viral infections in children with cancer and febrile neutropenia and children undergoing hematopoietic stem cell transplantation

Respiratory viral infections in children with cancer and febrile neutropenia and children undergoing hematopoietic stem cell transplantation

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