Infecciones del sistema nervioso central asociadas a dispositivos de derivación de LCR en niños, en un centro neuro-quirúrgico de referencia nacional

Abstract

Infecciones del sistema nervioso central asociadas a dispositivos de derivación de LCR en niños, en un centro neuro-quirúrgico de referencia nacional Central nervous system infections associated with CSF shunt devices in children, at a national reference hospital

Healthcare-Associated Ventriculitis in Children during COVID-19 Pandemic: Clinical Characteristics and Outcome of a First Infection

“…Other authors have not reported a greater rate of EVD [13] in comparison with VPS. Ventriculo-atrial shunts and ventriculo-pleural shunts are rarely used, and the reported rates of infections are high [8].…”

“…The placement of a ventricular shunt is an invasive therapeutic measure necessary to manage hydrocephalus in pediatric patients, mainly in children under 12 months of age (35.3%), which carries a high risk of complications [4,9,10]. HAV is one of the most feared post-surgical complications; rates of infection vary greatly in different centers, from 1% to 45% [4,[8][9][10][11][12][13]. At the beginning of and during the pandemic, HAV rates increased significantly, and the risk for patients was almost four times higher in 2021.…”

“…Besides the elevated costs, length of hospital stay, and risk of superinfections, the mortality rates can be as high as 20.4% in Turkey [10], which is similar to the result of the present study (17.6%). This rate is lower in Argentina (9%) [37] and nonexistent in Chile [13]. When comparing risk factors associated with adverse outcomes in adult and pediatric patients with HAV and meningitis, children have better outcomes.…”

“…In middle-and low-income countries, causative bacteria are mostly Gram-positive cocci (Staphylococcus epidermidis and other coagulase-negative species, Staphylococcus aureus, and Enterococcus spp. ), followed by enteric and non-fermenting Gram-negative bacilli (Escherichia coli, Klebsiella pneumoniae, Enterobacter spp., Pseudomonas aeruginosa, and Acinetobacter baumannii) [9,10,[13][14][15].…”

Measurement of cerebrospinal fluid lactate levels in pediatric patients with suspected ventriculoperitoneal shunt infection: A retrospective cohort study

“…The incidence is estimated to be between 10-20%, which varies according to the case de nition, studied period, etc [2,3]. In our center the incidence is 7.8% in the rst installation and 23% in the following ones [4].…”