Infección por HTLV post-trasplante renal

Mateos, Ainara Villafruela; Echevarría, Antón Arruza; Bazaco, Jesús Martín; Arin, Igor Azurmendi; Egurrola, J A Zabala; Peña, Carlos Pertusa

doi:10.4321/s0004-06142005001000011

Cited by 5 publications

References 2 publications

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Predominance of Human Lymphotropic T Cell Virus Type 2 Subtype b in Urban Populations of Argentina

Berini

Eirin

Delfino

et al. 2012

AIDS Research and Human Retroviruses

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Human T-lymphotropic virus subtype b (HTLV-2b) infection has been described among aborigines from Northern Argentina, while HTLV-2a has been described in an injecting drug user (IDU) from a Central region, similar to the situation in Spain, the United States, and Brazil. In this study, 22 of the 26 strains analyzed from blood donors and HIV-1(+) individuals were HTLV-2b (84.6%) clustering with Amerindian references, while 4 HIV-1(+) (15.4%) were HTLV-2a. HTLV-2a sequences were closely related to Brazilian references in contrast to the previous Argentinean IDU strain that clustered with Africans and Amerindians from North America. In summary, these findings show that HTLV-2b is the major strain circulating in an urban population of Argentina. HTLV-2a/b could have been introduced from endemic South American countries such as Brazil and because of contact with other populations such as IDUs from Europe despite its introduction due to the increasing internal migration of aborigines to large urban centers. Considering this results and recent data about the dissemination of HTLV-1 in residents of Buenos Aires city, new studies among non-at-risk groups for HTLV-1/2 infection should be performed.

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Predominance of Human Lymphotropic T Cell Virus Type 2 Subtype b in Urban Populations of Argentina

Berini

Eirin

Delfino

et al. 2012

AIDS Research and Human Retroviruses

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HTLV-1-associated myelopathy in a solid organ transplant recipient

2016

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Human T-cell lymphotropic virus type-1 (HTLV-1) is endemic in Japan, the Caribbean and in South American countries such as Ecuador. This virus is the cause of HTLV-1-associated myelopathy or tropical spastic paraparesis (HAM/TSP), a myelopathy characterised by chronic progressive paraparesis, spasticity and urinary symptoms. We report the case of a 40-year-old man who received a kidney transplant from a living donor and developed HAM/TSP, 24 months after transplant. The diagnosis was confirmed by detection of HTLV-1 in blood and cerebrospinal fluid by the ELISA and Western Blot tests. For myelopathy, the patient was treated with pulse methylprednisolone, but had poor response to treatment. We recommend that all patients receiving transplants and their donors who come from endemic countries be given a mandatory screening for HTLV-1 through an ELISA test, in an effort to inform candidates for renal transplantation of the potential risk of infection and the development of this disease.

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General Medical Evaluation of the Living Donor

McCauley¹,

Shaw-Stiffel²

2008

Living Donor Organ Transplantation(Softcover Edition for Special Sale)

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Infección por HTLV post-trasplante renal

Cited by 5 publications

References 2 publications

Predominance of Human Lymphotropic T Cell Virus Type 2 Subtype b in Urban Populations of Argentina

Predominance of Human Lymphotropic T Cell Virus Type 2 Subtype b in Urban Populations of Argentina

HTLV-1-associated myelopathy in a solid organ transplant recipient

General Medical Evaluation of the Living Donor

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