Infantile periarteritis nodosa with coronary and brachial aneurysms: A case diagnosed during life

Chamberlain, John L.; Perry, Lowell W.

doi:10.1016/s0022-3476(71)80439-0

Cited by 57 publications

(10 citation statements)

References 8 publications

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“…An invasive intervention may be necessary in the symptomatic patient. In the pediatric population, 'infantile PAN' or KD, associated with coronary aneurysms has been described with recovery and even regression of the aneurysms [24,25]. Outcomes of coronary artery aneurysms in PAN identified pre-mortem are not well described.…”

Section: Discussionmentioning

confidence: 99%

Giant coronary artery aneurysms in juvenile polyarteritis nodosa: a case report

et al. 2012

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Juvenile polyarteritis nodosa (PAN) is a rare, necrotizing vasculitis, primarily affecting small to medium-sized muscular arteries. Cardiac involvement amongst patients with PAN is uncommon and reports of coronary artery aneurysms in juvenile PAN are exceedingly rare. We describe a 16 year old girl who presented with fever, arthritis and two giant coronary artery aneurysms, initially diagnosed as atypical Kawasaki disease and treated with IVIG and methylprednisolone. Her persistent fevers, arthritis, myalgias were refractory to treatment, and onset of a vasculitic rash suggested an alternative diagnosis. Based on angiographic abnormalities, polymyalgia, hypertension and skin involvement, this patient met criteria for juvenile PAN. She was treated with six months of intravenous cyclophosphamide and high dose corticosteroids for presumed PAN related coronary vasculitis. Maintenance therapy was continued with azathioprine and the patient currently remains without evidence of active vasculitis. She remains on anticoagulation for persistence of the aneurysms. This case illustrates a rare and unusual presentation of giant coronary artery aneurysms in the setting of juvenile PAN.

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Section: Discussionmentioning

confidence: 99%

Giant coronary artery aneurysms in juvenile polyarteritis nodosa: a case report

et al. 2012

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“…Coronary artery ectasia or aneurysm in childhood may also result from an infantile polyarteritis (McMartin et al, 1974;Chamberlain and Perry, 1971). More recently a mucocutaneous lymph node syndrome in Japanese children has been noted to cause coronary artery aneurysms resem-bling infantile polyarteritis (Kato et al, 1975).…”

Section: Discussionmentioning

confidence: 99%

Coronary artery ectasia--a variant of occlusive coronary arteriosclerosis.

Swanton¹,

Thomas²,

Coltart³

et al. 1978

Heart

209

148

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“…Numerous investigators have noted that the arteritis of MCLS is both macroscopically and microscopically identical to that seen in infantile polyarteritis nodosa (1-3,15,17,18). Even among survivors of MCLS, coronary angiography has revealed coronary artery aneurysms (19)(20)(21) like those commonly seen in IPN (6,9,10,22).…”

Section: Discussionmentioning

confidence: 99%

Polyarteritis nodosa in childhood

Ettlinger

Nelson

Burke

et al. 1979

Arthritis & Rheumatism

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The clinical and pathologic findings of 2 infants and 7 older children with polyarteritis nadosa who were autopsied are reported. The most frequent clinical features included prolonged high fever, skin rash, abdominal symptoms, leukocytosis, proteinuria, and signs of either cardiac or renal failure. The 2 infants died of cardiac arrest, whereas renal or neurologic involyement was the most common cause of death in the older children. A consistent finding at autopsy was arteritis of the epicardial coronary arteries.

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Infantile periarteritis nodosa with coronary and brachial aneurysms: A case diagnosed during life

Cited by 57 publications

References 8 publications

Giant coronary artery aneurysms in juvenile polyarteritis nodosa: a case report

Giant coronary artery aneurysms in juvenile polyarteritis nodosa: a case report

Coronary artery ectasia--a variant of occlusive coronary arteriosclerosis.

Polyarteritis nodosa in childhood

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