Infantile hookworm disease

Bhatia, Vidyut; Das, Manoj; Kumar, Pawan; Arora, Narendra K.

doi:10.1007/s13312-010-0033-2

Cited by 10 publications

(9 citation statements)

References 8 publications

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“…In the pediatric population, hookworm infection typically spreads among children when they start to crawl or walk. In newborn or infancy, on the contrary, it is rare, and most of the cases reported in literature are from tropical and subtropical countries, especially Nepal, China, India, and Africa [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Hookworm infection in infants: a case report and review of literature

et al. 2021

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Background Hookworm infections (Necator americanus, Ancylostoma duodenale) are common in rural areas of tropical and subtropical countries. Human acquisition results from direct percutaneous invasion of infective larvae from contaminated soil. Overall, almost 472 million people in developing rural countries are infected. According to simulation models, hookworm disease has a global financial impact of over US$100 billion a year. Hookworm infection in newborn or infancy is rare, and most of the cases reported in literature are from endemic countries. Here, we describe the case of an infant with an Ancylostoma duodenale infection and review the literature currently available on this topic. Case presentation An Italian 2-month-old infant presented with vomit and weight loss. Her blood exams showed anemia and eosinophilia and stool analysis resulted positive for hookworms’ eggs, identified as Ancylostoma duodenale with real time-PCR. Parasite research on parents’ stools resulted negative, and since the mother travelled to Vietnam and Thailand during pregnancy, we assumed a transplacental transmission of the infection. The patient was treated successfully with oral Mebendazole and discharged in good conditions. Discussion Hookworm helminthiasis is a major cause of morbidity in children in the tropics and subtropics, but rare in developed countries. Despite most of the patients is usually asymptomatic, children are highly exposed to negative sequelae such as malnutrition, retarded growth and impaired cognitive development. In infants and newborns, the mechanism of infection remains unclear. Although infrequent, vertical transmission of larvae can occur through breastfeeding and transplacentally. Hookworm infection should be taken into account in children with abdominal symptoms and unexplained persistent eosinophilia. The treatment of infants infected by hookworm has potential benefit, but further studies are needed to define the best clinical management of these cases.

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Section: Introductionmentioning

confidence: 99%

Hookworm infection in infants: a case report and review of literature

et al. 2021

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“…In India, there were case reports of a 12 week and 8month infants who had melana stools with upper GI endoscopy showing worms attached to the intestine. 11 A twelve day old Nepalese infant developed severe anaemia owing to hook worm infestation and responded well to mebendazole 12 . In Africa there has been reports of hookworm infestation in a 3 and 4 month old in Nigeria and Uganda respectively, presenting with melena and severe anemia with fever 13,14 .…”

Section: Discussionmentioning

confidence: 99%

Recurrent severe anaemia caused by multiple infestation with anklylostoma duodenale and entamoeba histolytica in a 5 months old female Nigerian infant

Akintan¹,

Emokpae²,

Mabogunje³

et al. 2016

Nig. J. Paed.

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Worm and parasitic infestation is a common problem in children with most occurring in school age. Low socioeconomic status and poor sanitary hygiene has been associated with worm infesetation. Though it is rare in infancy, there had been reports in these group of children. However there has been no documented case of multiple infestation in infancy. We hereby report an infant with recurrent anemia and melena and bloody stools caused by anklylostomaduodenale and entamoebahistolytica

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“…Whereas Necator americanus accounts for most of the world's cases of human hookworm infections, in Uttar Pradesh and West Bengal States, and presumably elsewhere in India, mixed infections with both N. americanus and Ancylostoma duodenale also occur, as well as pure A. duodenale infections [14]. A. duodenale has also been identified as a cause of infantile hookworm [15]. In Pakistan, wastewater used in agriculture was found to be a significant risk factor for hookworm [16].…”

Section: Helminth Infectionsmentioning

confidence: 99%