Infantile digital fibromatosis: case report

Gomes, Eduardo Amaral; Saliba, Gustavo Augusto Matos; Saliba, Jamil José

doi:10.5935/2177-1235.2014rbcp0036

Cited by 1 publication

(2 citation statements)

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“…A viral aetiology was initially suspected because of the presence of cytoplasmic inclusions but polymerase chain reaction and electron microscopy have ruled out this possibility. 2,4,5,6 Inclusions are now known to be composed of densely packed vimentin and actin filaments and is thought to arise due to aberrant assemblage of microfilaments in myofibroblasts and smooth muscle cells. 7 The tumour may be single or multiple, firm or gelatinous in consistency [1][2][3][4][5][6][7] .…”

Section: Discussionmentioning

confidence: 99%

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Congenital infantile digital fibromatosis: a case report and review of the literature

2020

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Infantile digital fibromatosis (IDF), also called inclusion body fibromatosis is an uncommon benign tumour occurring in the digits of young children. In about a third of cases, it is congenital and the diagnosis is based on the presence of peculiar intracytoplasmic inclusions on histology. Recurrence rate post-surgery is high. However, spontaneous regression has been reported. We present a case of a 5-month-old infant who had excision of a right second toe mass, which has been present from birth. Histological examination revealed this to be infantile digital fibromatosis. To the best of our knowledge, no report of this has been made in Nigeria. It is important that this diagnosis be entertained in young children with masses on the digits as this will influence the management instituted. Keywords: Fibromatosis; digits; inclusion body.

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Section: Discussionmentioning

confidence: 99%

“…[2][3][4] Intracytoplasmic inclusions can be seen on H&E at high power. [1][2][3][4][5][6] Histochemical stains are useful in making a diagnosis. 2 The cytoplasmic inclusions are eosinophilic with Masson's Trichrome stain, which was used for this case.…”

Section: Discussionmentioning

confidence: 99%