Infantile chlamydial pneumonia—A review based on 115 cases

Schaad, Urs B.; Rossi, E

doi:10.1007/bf00441134

Cited by 19 publications

(3 citation statements)

References 26 publications

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“…The organism has been isolated from MEE of children and infants previously (Tipple et al, 1979;Chang et al, 1982). Middle ear abnormalities and otitis media have been associated with proven chlamydial infections of the eyes and lungs (Gow, Ostler and Schachter, 1974;Schachter, Grossman, Holt, Sweet, Goodner and Mills, 1979;Khurana, 1980;Schaad and Rossi, 1982). However, C. trachomatis has never been isolated from the middle ear in a trachoma endemic population.…”

Section: Discussionmentioning

confidence: 99%

MICROBIOLOGY OF CHRONIC OTITIS MEDIA WITH EFFUSION AMONG AUSTRALIAN ABORIGINAL CHILDREN: ROLE OF CHLAMYDIA TRACHOMATIS

Dawson

Coelen

Murphy

et al. 1985

Aust J Exp Biol Med

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Summary Serum, eye secretions, post‐nasal swabs, external ear swabs and middle ear effusions (MEE) were collected from 131 Australian Aboriginal children with chronic otitis media with effusion (COME). The children were all resident in a trachoma endemic region. Chlamydia trachomatis was recovered from the MEE of 2 children. Probable bacterial pathogens were isolated from 34 (12·7%) ears. The remainder were sterile (52·4%) or contained normal skin flora (34·9%). Serum and secretions were examined by the micro‐immunofluorescent technique for the presence, titre and serotype of anti‐chlamydial antibody. Antibody, predominantly of the C serotype, was found in a high percentage of sera (80%) and secretions (approximately 50%). This serotype is associated with ocular trachoma. It is concluded that C. trachomatis is associated with COME among some Aboriginal children in this trachoma endemic area.

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Section: Discussionmentioning

confidence: 99%

MICROBIOLOGY OF CHRONIC OTITIS MEDIA WITH EFFUSION AMONG AUSTRALIAN ABORIGINAL CHILDREN: ROLE OF CHLAMYDIA TRACHOMATIS

Dawson

Coelen

Murphy

et al. 1985

Aust J Exp Biol Med

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“…There are no data on cough recording in the human fetus (Chang and Widdicombe, 2007) and at birth, cough seems to be absent, or rarely present as part of the laryngeal chemoreflex (Thach, 2007). As maturation progresses, cough response to stimulation by fluid contact with the laryngeal mucosa increases (Perkett and Vaughan, 1982; Pickens et al, 1988), cough being reported below 1 month of age in infants with respiratory tract infection (Schaad and Rossi, 1982) or foreign body inhalation (Singh et al, 1999). Cough becomes the most frequent respiratory symptom during the first years of life, but objective data on incidence of the cough reflex in that age range are lacking, mainly because infants and young children lack the active cooperation required to perform capsaicin sensitivity test.…”

Section: Physiological Mechanisms Of Cough During Developmentmentioning

confidence: 99%

What is chronic cough in children?

et al. 2014

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The cough reflex is modulated throughout growth and development. Cough—but not expiration reflex—appears to be absent at birth, but increases with maturation. Thus, acute cough is the most frequent respiratory symptom during the first few years of life. Later on, the pubertal development seems to play a significant role in changing of the cough threshold during childhood and adolescence resulting in sex-related differences in cough reflex sensitivity in adulthood. Asthma is the major cause of chronic cough in children. Prolonged acute cough is usually related to the long-lasting effects of a previous viral airway infection or to the particular entity called protracted bacterial bronchitis. Cough pointers and type may orient toward specific etiologies, such as barking cough in croup or tracheomalacia, paroxystic whooping cough in Pertussis. Cough is productive in protracted bacterial bronchitis, sinusitis or bronchiectasis. Cough is usually associated with wheeze or dyspnea on exertion in asthma; however, it may be the sole symptom in cough variant asthma. Thus, pediatric cough has particularities differentiating it from adult cough, so the approach and management should be developmentally specific.

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“…7 So, it is of vital significance to choose a quickest, highly sensitive and specific laboratory index for early diagnosis of children with severe pneumonia for early application of treatment methods corresponding to different pathogen infections. [8][9][10][11] In recent years, PCT has been regarded as a very important biomarker for the diagnosis of systemic bacterial infection. Procalcitonin is a pro-hormone, and studies show that their serum levels can be used to distinguish sepsis from systemic inflammatory response.…”

Section: Introductionmentioning

confidence: 99%