Infantile acropustulosis in internationally adopted children

Good, Laurie M.; Good, Travis J; High, Whitney A.

doi:10.1016/j.jaad.2010.06.047

Cited by 28 publications

(7 citation statements)

References 16 publications

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“…[17][18][19][20][21] Infantile acropustulosis, which in most cases occur after scabies infestation, may greatly mimic scabies due to the frequent presence of acral vesiculopustular lesions in both conditions. 22,23 Therefore, a careful clinical examination is mandatory, and frequent signs such as burrows (even if only 1), axillary nodules, and involvement of the soles, dorsum forefoot, and scalp should be tracked.…”

Section: Discussionmentioning

confidence: 99%

Clinical Phenotype of Scabies by Age

et al. 2014

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WHAT'S KNOWN ON THIS SUBJECT:Scabies is a frequent cause of consultation and has recently been classified as a neglected disease. The clinical presentation seems to be linked with age, although no specific study has aimed to delineate the clinical spectrum of scabies in infants and children.WHAT THIS STUDY ADDS: Scabies in infants and children has distinct clinical features. This prospective observational study found that infants were more likely to have relapse, nodules, and to present involvement with extremities, face, and scalp, arguing for specific cares in this age group. abstract OBJECTIVE: Scabies has a clinical presentation that seems to vary according to age. We conducted a prospective study with the goal of delineating the clinical presentation of the disease into 3 groups of age: infants, ,2 years; children, 2 to 15 years; and adults, .15 years. METHODS:This trial was a prospective, multicenter observational study in consecutive patients with a confirmed diagnosis of scabies who were seen in 13 French Departments of Dermatology and Pediatric Dermatology between April 2010 and April 2011. A standardized questionnaire was completed for each patient. To identify factors associated with patient age, comparisons between the 3 age groups were conducted by using univariate and multivariate multinomial logistic regression analyses.RESULTS: A total of 323 individuals were included; the gender ratio (female:male) was 1.2:1. In univariate analysis, infants were more likely to have facial involvement. In multivariate logistic regression, relapse was more frequent in children (odds ratio [OR] .51]) involvement were also found to be independently associated with the age group ,2 years. CONCLUSIONS:There is a specific clinical presentation of scabies in infants and children. Taking into account these specificities may be helpful for the early diagnosis and the identification of cases to prevent the propagation of the disease. Pediatrics 2014;133:e910-e916 AUTHORS:

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Section: Discussionmentioning

confidence: 99%

Clinical Phenotype of Scabies by Age

et al. 2014

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“…Some suggest that the majority of international adoptees with a history of institutional living are infected (Good et al, 2011). Adoptive parents often acquire medications and presumptively or empirically treat children in-country.…”

Section: Systemic Diseases With Prominent Skin Manifestationsmentioning

confidence: 99%

“…Secondary bacterial infection is common in the developing world, and in these cases, cultures are essential to choosing appropriate antibiotic treatment (Zhu et al, 2010) (see section on SSTIs). Persistent papules or pustules following treatment for scabies should trigger suspicion for infantile acropustulosis (Good et al, 2011) (see below).…”

Section: Systemic Diseases With Prominent Skin Manifestationsmentioning

confidence: 99%

Dermatologic conditions in internationally adopted children

Whitaker-Worth

Bayart

Benedetti

2015

International Journal of Women's Dermatology

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Over 200,000 children have been adopted into United States (US) families from abroad since the year 2000. Health care providers who care for children adopted internationally should be aware of the spectrum of illnesses seen in this population, and should be prepared to encounter potentially unusual situations. An appreciation for the unique pre-adoption exposures and vulnerabilities inherent in international adoption is critical for proper diagnosis and treatment of this heterogeneous group of children. It is important to consider the impact of potential early childhood stressors such as nutritional, sensory, and emotional deprivation, trauma and abuse, as well as prenatal exposures to drugs, alcohol, and infectious diseases. Providers must also take into account international variation in health care practices, including immunization, treatment, surgical, and hygiene standards. The differential diagnosis for cutaneous eruptions in children adopted internationally is broad and must encompass endemic systemic illnesses with skin manifestations, such as measles, tuberculosis, leprosy, and congenital syphilis, and primary dermatologic diseases such as scabies and bacterial and fungal infections. The importance of maintaining a broad differential and open mind when addressing the dermatologic needs of these children cannot be overemphasized.

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“…IA is a recurrent, self-limited, pruritic, vesiculopustular eruption on the distal extremities occurring in young children (typically black infants) during the first 2–3 years of life. Newly described in 1979,1 IA remains a poorly understood disease as demonstrated by the frequency of misdiagnoses 2. The onset is from birth to one year of age, with spontaneous resolution occurring between the ages of two and three years.…”

mentioning

confidence: 99%

“…This process resolves on its own after an evolution of a few years, without residual problems. The intensity and the duration of IA attacks diminish with each recurrence 2 3. The main differential diagnosis of IA includes scabies,4 erythema toxicum neonatorum and transient neonatal pustular melanosis.…”

mentioning

confidence: 99%