Infant with Granulocytic Sarcoma of the Ovary: An Unusual Case Presentation of Acute Myelogenous Leukemia (M6)

More Than Meets the Eye: A Presentation of Extramedullary Infiltration (AML-M7)

“…Generally speaking, granulocytic sarcomas occur most often in the bones of the skull, sternum, or ribs and occasionally in soft tissues around the dura, sinuses, and orbit. 1 Skin and lymph nodes are common sites as well. 1 Malignant cells are thought to originate in bone marrow; these cells are believed to spread via Haversian canals and accumulate in the periosteum, resulting in soft-tissue masses.…”

“…1 Skin and lymph nodes are common sites as well. 1 Malignant cells are thought to originate in bone marrow; these cells are believed to spread via Haversian canals and accumulate in the periosteum, resulting in soft-tissue masses.…”

“…Some investigators suggest focal radiation therapy to be of significant value in preventing extramedullary relapse in these patients. 1 Whereas the outcome of children with extramedullary infiltration is generally thought to be poor, other studies suggest the contrary. 3 A study by Byrd and colleagues 4 revealed that patients with granulocytic sarcoma achieved a complete remission rate of 50% versus 92% achieved in patients without granulocytic sarcoma.…”