Abstract:RATIONALE: Some studies suggest that the BAT more accurately predicts clinical peanut allergy than skin testing or serum IgE levels, potentially reducing the need for OFCs. However, basophils are not stable ex vivo and activation testing must take place within 3-4 hours of sample collection to achieve reliable results, thus excluding this test from most clinical settings. We tested a novel BAT prototype methodology developed by Beckman-Coulter, which can be done in the clinic and shipped to a central lab, to e… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.