Infant Mitral Valve Replacement: Current State of the Art

Overman, David M.; Moga, Francis X.; Graham, Gabriel; Dearani, Joseph A.; MacIver, Robroy

doi:10.1053/j.pcsu.2023.01.001

Cited by 3 publications

(1 citation statement)

References 23 publications

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“…Furthermore, classic bioprosthetic valves present the same size issue as mechanical valves, especially since some models have even higher profiles leading to problems such as left ventricular outflow tract obstruction [ 8 ]. Particularly in very young children with annular hypoplasia, bovine jugular vein conduits (Melody valve; Medtronic) could represent an eligible alternative with good early outcomes as well as the possibility of subsequent valve expansion delaying redo MV replacement [ 9 , 10 ]. This procedure could be used as a bridge therapy to allow growth of the mitral annulus and following fitting of a size appropriate mechanical prosthesis later in life [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

Long-term outcomes following mitral valve replacement in children at heart center Leipzig: a 20-year analysis

Schumacher,

Marin-Cuartas,

Aydin

et al. 2024

J Cardiothorac Surg

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Background Although mitral valve repair is the preferred surgical strategy in children with mitral valve disease, there are cases of irreparable severe dysplastic valves that require mitral valve replacement. The aim of this study is to analyze long-term outcomes following mitral valve replacement in children in a tertiary referral center. Methods A total of 41 consecutive patients underwent mitral valve replacement between February 2001 and February 2021. The study data was prospectively collected and retrospectively analyzed. Primary outcomes were in-hospital mortality, long-term survival, and long-term freedom from reoperation. Results Median age at operation was 23 months (IQR 5–93), median weight was 11.3 kg (IQR 4.8–19.4 kg). One (2.4%) patient died within the first 30 postoperative days. In-hospital mortality was 4.9%. Four (9.8%) patients required re-exploration for bleeding, and 2 (4.9%) patients needed extracorporeal life support. Median follow-up was 11 years (IQR 11 months − 16 years). Long-term freedom from re-operation after 1, 5, 10 and 15 years was 97.1%, 93.7%, 61.8% and 42.5%, respectively. Long-term survival after 1, 5, 10 and 15 years was 89.9%, 87%, 87% and 80.8%, respectively. Conclusion If MV repair is not feasible, MV replacement offers a good surgical alternative for pediatric patients with MV disease. It provides good early- and long-term outcomes.

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Section: Discussionmentioning

confidence: 99%