Industry, occupation, and exposure history of mesothelioma patients in the U.S. National Mesothelioma Virtual Bank, 2006–2022

Occupational and Environmental Asbestos Exposure and Survival of Patients with Asbestos-Related Cancer: A Follow-Up Study on Patients with Malignant Mesothelioma and Asbestos-Related Lung Cancer in Korea

“…The relationship between asbestos exposure and the survival of patients with asbestos-related cancers has been explored in several previous studies, but the results have been inconsistent. Studies conducted by Flores et al [ 22 ], Gao et al [ 10 ], and Noelle et al [ 17 ] indicated decreased survival in patients with cancers exposed to asbestos compared to those unexposed. In contrast, studies by Berardi et al [ 23 ], Nojiri et al [ 24 ], and Gorini et al [ 25 ] found no significant association between asbestos exposure and patient survival in asbestos-related cancer cases.…”

“…Another limitation in the existing research is the approach to investigating asbestos exposure history. Most of the previous studies focused solely on occupational asbestos exposure, with only one exploring the specific occupational settings of exposure [ 10 ]. Conversely, our study indicates that not just occupational asbestos exposure, but also the duration of work and proximity to the exposure source, can influence patient survival.…”

“…However, it has been recognized that some patients with asbestos-related cancers can survive significantly longer than the average [ 7 , 8 ]. Previous studies have re-ported that demographic characteristics (such as gender, age, race, and socioeconomic level) [ 9 , 10 , 11 , 12 , 13 ], lifestyle behaviors (like smoking) [ 12 , 14 ], and specific genetic factors [ 9 , 15 ] are associated with survival in patients with asbestos-related cancers. Identifying which factors are associated with a patient’s survival is important to determine patients at high risk of death.…”

“…Recent studies have suggested that characteristics of asbestos exposure may influence the survival of patients with malignant mesothelioma and asbestos-related lung cancer. Gao et al analyzed data from 748 patients in the US Na-tional Mesothelioma Virtual Bank and found that among industries where malignant mesothelioma was documented, manufacturing and construction were the most frequent [ 10 ]. Noelle et al analyzed data from 702 lung cancer patients at the Comprehensive Cancer Center Leon Berard in Lyon, France, and reported that the survival of lung cancer patients occupationally exposed to asbestos might be shorter compared to that of those not exposed [ 17 ].…”

Air pollution and survival in patients with malignant mesothelioma and asbestos-related lung cancer: a follow-up study of 1591 patients in South Korea

“…These included age at diagnosis (continuous), sex (male and female), smoking status (never-smoker, past smoker, current smoker, and unknown), cancer cell type for malignant mesothelioma (epithelioid, sarcomatoid, and biphasic) and lung cancer (adenocarcinoma, squamous cell, small cell, large cell, and others), type of treatment (surgery, radiotherapy, and chemotherapy), and the month of diagnosis (continuous) to control for seasonal variation effects. Additionally, based on recent preliminary research showing variations in patient survival depending on the type of asbestos exposure [ 21 , 22 ], we adjusted for asbestos exposure modalities (environmental exposure, occupational exposure, and co-exposure).…”