In a multiagent system, the semantic interaction between agents is an important aspect affecting multi-intelligence. The purpose of interaction is to reasonably arrange task objectives and behaviors through information sharing and communication interaction, so as to maximize the overall performance of multiagent system. This paper analyzes the communication and interaction process between agents from the perspective of semantic layer and introduces the BDI (belief, desire, intention) model of agent’s thinking state into the communication and interaction process. Furthermore, we propose a multiagent semantic interaction strategy model based on a large-scale intelligent sensor network, which supports various types of negotiation and interaction on the basis of basic interaction behavior to solve the problem of information operational conflicts. In addition, this paper limits the scale of historical information through the definition of equivalence and the merging theorem of history, and it uses reinforcement learning algorithm to detect possible conflicts and delay communication and makes rational use of limited resources to improve system revenue and coordination efficiency. The experimental results show that compared with the previous methods such as debate and negotiation, the strategy model can realize the flexible interaction based on scene and is more practical. At the same time, the existence of reinforcement learning improves the efficiency analysis and the convergence performance of semantic interaction strategy.