Industrial applications of thermophilic/hyperthermophilic enzymes

Bajpai, Pratima

doi:10.1016/b978-0-443-19197-8.00016-5

Cited by 1 publication

(1 citation statement)

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“…These metabolites are organic compounds that are not directly involved in the growth of microorganisms but often possess valuable properties. Hot springs have proven to be a rich source of diverse secondary metabolites with potential applications in various industries, including pharmaceuticals, agriculture, and biotechnology [2,6]. The discovery and characterization of these secondary metabolites from thermophiles found in hot springs hold immense promise for the development of novel bioactive compounds.…”

Section: Introductionmentioning

confidence: 99%

Unveiling Antibacterial Potential and Physiological Characteristics of Thermophilic Bacteria Isolated from a Hot Spring in Iran

Rafiee,

Jalili Tabaii,

Moradi

et al. 2024

Microorganisms

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The increasing worldwide demand for antimicrobial agents has significantly contributed to the alarming rise of antimicrobial resistance, posing a grave threat to human life. Consequently, there is a pressing need to explore uncharted environments, seeking out novel antimicrobial compounds that display exceptionally efficient capabilities. Hot springs harbor microorganisms possessing remarkable properties, rendering them an invaluable resource for uncovering groundbreaking antimicrobial compounds. In this study, thermophilic bacteria were isolated from Mahallat Hot Spring, Iran. Out of the 30 isolates examined, 3 strains exhibited the most significant antibacterial activities against Escherichia coli and Staphylococcus aureus. Furthermore, the supernatants of the isolated strains exhibited remarkable antibacterial activity, displaying notable resistance to temperatures as high as 75 °C for 30 min. It was determined that the two strains showed high similarity to the Bacillus genus, while strain Kh3 was classified as Saccharomonospora azurea. All three strains exhibited tolerance to NaCl. Bacillus strains demonstrated optimal growth at pH 5 and 40 °C, whereas S. azurea exhibited optimal growth at pH 9 and 45 °C. Accordingly, hot springs present promising natural reservoirs for the isolation of resilient strains possessing antibacterial properties, which can be utilized in disease treatment or within the food industry.

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Section: Introductionmentioning

confidence: 99%