Inductive Integrated Biosensor With Extended Operative Range for Detection of Magnetic Beads for Magnetic Immunoassay

Beninato, Angela; Sinatra, Valentina; Tosto, Giuseppe; Castagna, Maria Eloisa; Petralia, Salvatore; Conoci, Sabrina; Baglio, Salvatore

doi:10.1109/tim.2016.2619000

Cited by 11 publications

(7 citation statements)

References 23 publications

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“…They have been widely used in biomedicine field to separate and detect various biomolecules. Combined with magnetic labeling technology, the use of magnetic sensors to analyze and detect biomolecules has become a research hotspot in biomedical field 14,15 . In this platform, superparamagnetic beads were used to label the corresponding biomolecules.…”

Section: Introductionmentioning

confidence: 99%

The progress of magnetic sensor applied in biomedicine: A review of non‐invasive techniques and sensors

Cheng

Alhalili

et al. 2020

J Chinese Chemical Soc

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With the rapid development of sensing technology, it has attracted tremendous interests in the field of biomedicine because of its good biocompatibility, reliability, and safety. In comparison to other sensors, magnetic sensor has a broad application prospect in biomedical field due to its high sensitivity, small size, and intriguing non‐invasive detection property. The purpose of this review is to discuss the applications of magnetic sensors in the biomedical field. First, some widely used magnetic sensors are reviewed based on their working principle and characteristics. Then, the applications of magnetic sensors in biomedical field are introduced from the aspects of magnetic label‐based bioassays, detection of biological movement, and biology magnetism. Finally, the future development direction and prospect of magnetic sensors in biomedical field are prospected. This review will provide a general outlook for the applications of magnetic sensors in biomedicine.

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Section: Introductionmentioning

confidence: 99%

The progress of magnetic sensor applied in biomedicine: A review of non‐invasive techniques and sensors

Cheng

Alhalili

et al. 2020

J Chinese Chemical Soc

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“…In applications that need rapid decision-making [10][11][12] the advantages of the lateral flow method stand up, even when sometimes its sensitivity is lower than that of other immunoanalytical techniques (e.g., the enzyme-linked immunosorbent assay). To improve sensitivity and reduce the limits of detection, some ideas, such as chemical signal enhancement, [13][14][15] test design, 16 or more sensitive transducers or read-out instrumentation 17 have been explored.…”

Section: Introductionmentioning

confidence: 99%

Improved magnetic lateral flow assays with optimized nanotags for point-of-use inductive biosensing

Salvador

Gallo-Córdova

Moyano

et al. 2020

Analyst

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“…Inductance converters, on the other hand, are used in many applications for the measurement of inductances and magnetic material properties, for the biomagnetic signal detection, detection of magnetic beads, detection of microscale magnetic particles from macroscale materials, etc. [3,4,5]. The measured physical parameters are correlated to the material’s composition or measured physical characteristics through the known relation between physical parameters and chemical properties to measure magnetic material properties.…”

Section: Introductionmentioning

confidence: 99%

Highly Enhanced Inductance Sensing Performance of Dual-Quartz Crystal Converter

Matko

Milanovič

2019

Sensors

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This paper presents ways of inductance sensitivity improvement in a quartz crystal converter for low inductance measurement. To improve the converter’s sensitivity, two quartz crystals that were connected in parallel and additional capacitance connected to the two quartz crystals in the oscillator’s circuit are used. The new approach uses a converter with special switchable oscillator and multiplexer switches to compensate for the crystal’s natural temperature-frequency characteristics and any other influences, such as parasitic capacitances and parasitic inductances, which reduce them to a minimum. The experimental results demonstrate improved sensitivity and well-compensated dynamic temperature influence on the converter’s output frequency. The fundamental quartz crystal frequency-temperature characteristics in the temperature range between 0–40 °C are simultaneously compensated. Furthermore, the converter enables the measurement of the influence of its own hysteresis at different values of inductances at the selected sensitivity by parallel capacitances connected either to the single- or dual-quartz crystal unit. The results show that the converter converting inductances in the range between 85–100 μH to a frequency range between 1–150 kHz only has ±0.05 ppm frequency instability (during the temperature change between 0–40 °C), which gives the converter a resolution of 1 pH. As a result, the converter can be applied where low inductance measurement, nondestructive testing, impedance change measurement, and magnetic material properties measurement are important.

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Inductive Integrated Biosensor With Extended Operative Range for Detection of Magnetic Beads for Magnetic Immunoassay

Cited by 11 publications

References 23 publications

The progress of magnetic sensor applied in biomedicine: A review of non‐invasive techniques and sensors

The progress of magnetic sensor applied in biomedicine: A review of non‐invasive techniques and sensors

Improved magnetic lateral flow assays with optimized nanotags for point-of-use inductive biosensing

Highly Enhanced Inductance Sensing Performance of Dual-Quartz Crystal Converter

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