Induction of Superovulation in Domestic Ruminants

Gonzalez, Fredy Andrey Lopez; Calero, P.; Beckers, Jean‐François

doi:10.1007/0-306-46887-5_12

Cited by 6 publications

(14 citation statements)

References 74 publications

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“…In addition, hMG has been shown to produce a comparable ovulation rate (10 vs. 9.9; p > 0.05), rate of transferable embryos (84% vs. 80%), and fertilization rate (86% vs. 95%; (p > 0.05) to that of FSH [31]. Similar comparable responses of hMG with FSH have also been obtained [61], and in one case, hMG produced higher ovulation rates and improved embryo quality than obtained through FSH [14]. However, this hormone has not been extensively utilized for superstimulation due to its high cost [62].…”

Section: Other Rarely Used Hormonesmentioning

confidence: 61%

“…Although eCG is cost-effective and can easily be applied to an open flock with minimal bodily stress [ 54 ], dose-dependent responses may lead to an increased number of persistent large follicles [ 54 ] and premature corpus luteum regression [ 55 ]. Furthermore, it also influences the pattern of steroidal hormone synthesis, thus disrupting sperm and gamete transport, as well as preimplantation embryo development [ 14 ]. To potentiate the ovarian response, the combination of eCG and FSH has been applied, and increased ovulation rate (14.2 vs. 6.2; p < 0.05) and embryonic recovery (5.2 vs. 1.0; p < 0.05) was observed [ 53 ].…”

Section: Hormones For Superovulationmentioning

confidence: 99%

“…However, this technology is still not completely applicable in sheep due to their relatively small physical size and complexity regarding the anatomy of the tightly folded cervix, which inhibits rectal manipulation [ 12 , 13 ]. The most challenging aspects of this technology is the inconsistent ovarian responses of donor sheep to various hormonal treatments, difficulty in embryo recovery, and the reproductive status of the recipient when transferring viable embryos [ 14 , 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

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Towards Improving the Outcomes of Multiple Ovulation and Embryo Transfer in Sheep, with Particular Focus on Donor Superovulation

Khan

Jamal

et al. 2022

Veterinary Sciences

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Considerable improvements in sheep multiple ovulation and embryo transfer (MOET)protocols have been made; however, unlike for cattle, MOET is poorly developed in sheep, and thus has not been broadly applicable as a routine procedure. The tightly folded nature of the ewe cervix, the inconsistent ovarian response to various superovulatory treatments, and the requirement of labor to handle animals, particularly during large-scale production, has limited the implementation of successful MOET in sheep. Moreover, several extrinsic factors (e.g., sources, the purity of gonadotrophins and their administration) and intrinsic factors (e.g., breed, age, nutrition, reproductive status) severely limit the practicability of MOET in sheep and other domestic animals. In this review, we summarize the effects of different superovulatory protocols, and their respective ovarian responses, in terms of ovulation rate, and embryo recovery and transfer. Furthermore, various strategies, such as inhibin immunization, conventional superovulation protocols, and melatonin implants for improving the ovarian response, are discussed in detail. Other reproductive techniques and their relative advantages and disadvantages, such as artificial insemination (AI), and donor embryo recovery and transfer to the recipient through different procedures, which must be taken into consideration for achieving satisfactory results during any MOET program in sheep, are also summarized in this article.

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Section: Other Rarely Used Hormonesmentioning

confidence: 61%

Section: Hormones For Superovulationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Towards Improving the Outcomes of Multiple Ovulation and Embryo Transfer in Sheep, with Particular Focus on Donor Superovulation

Khan

Jamal

et al. 2022

Veterinary Sciences

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“…Embryo transfer (ET) is a reproductive biotechnology used to multiply the number of animals of high genetic value (Bó et al, 2004) to accelerate animal genetic improvement (Nogueira et al, 2002). Superovulatory (SOV) techniques are involved in ET programs to increase ovulation rate as well as the yield of transferable quality embryos (Armstrong, 1993;González et al, 2001). However, large variation in the SOV response still remains as a major hindrance to the routine production of embryos from cattle by conventional methods (González et al, 2001).…”

Section: Introductionmentioning

confidence: 99%

“…Superovulatory (SOV) techniques are involved in ET programs to increase ovulation rate as well as the yield of transferable quality embryos (Armstrong, 1993;González et al, 2001). However, large variation in the SOV response still remains as a major hindrance to the routine production of embryos from cattle by conventional methods (González et al, 2001). Some variation can be attributed to hormone treatments (Mapletoft et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

Reuse of norgestomet implants in an eCG-based superovulation protocol administered to Nelore (Bos taurus indicus) cows

et al. 2011

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This study assessed the reuse of norgestomet implants in Nelore cows that were superstimulated with eCG. In a crossover design trial, eight cows were randomly divided into two experimental groups and twice superstimulated: Group 1half of the cows received a new norgestomet implant and 2 mg estradiol benzoate (EB) on Day 0; Group 2remaining cows received two once-used norgestomet implants and 2 mg EB also on Day 0. On Day 4 all cows received a single dose of 2000 IU eCG, and on Day 6 cows were treated with two doses of PGF 2α 12 h apart. Ovulation was induced with 12.5 mg pLH 12 h after implant withdrawal (on Day 7), and fixedtime artificial inseminations were carried out 12 and 24 h later. Seven days after pLH injection embryos were recovered and blood samples were taken to determine circulating progesterone. Ultrasound examinations were performed at pLH administration and at embryo recovery. The number of large follicles (≥8 mm) was greater (Pb 0.05) in Group 1 (17.1 ± 1.8) than in Group 2 cows (9.7± 1.6). The mean number of corpora lutea was greater (Pb 0.05) for Group 1 (13.8 ± 1.8) as compared to Group 2 cows (5.4± 1.0) and the percentage of large follicles that ovulated following pLH administration also differed (Pb 0.05) between treatments (80.3% and 53.8% for cows in Groups 1 and 2, respectively). However, no differences (PN 0.05) were found between treatments (respectively, for Group 1 and Group 2 cows) in the follicle diameter (10.5 ± 1.6 and 10.2± 1.7 mm), corpus luteum (CL) diameter (15.7 ± 1.8 and 14.4± 1.7 mm), CL volume (2232 ± 1356 and 1893± 1828 mm 3), ova/embryos recovered (6.3± 1.1 and 4.0 ± 1.9), transferable embryos (4.0± 1.8 and 2.5 ± 1.0) and plasma progesterone concentration (36.1 ± 8.3 and 35.1± 6.9 ng/mL). In conclusion, the stimulatory effects on the ovaries provided by the use of two onceused implants were less intense than the ones verified after using a new implant.

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Respuesta ovárica y embrionaria de dos protocolos de superovulación en bovinos altoandinos Pardo Suizo

Luján¹,

Zamora²,

Curo³

et al. 2023

Rev. Investig. Altoandin.

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El objetivo fue evaluar la respuesta ovárica y embrionaria de dos protocolos hormonales de superovulación en bovinos altoandinos Pardo Suizo. Se utilizaron 4 vacas donantes mediante un diseño de series temporales interrumpidas con replicaciones cambiadas donde cada vaca fue sometida a dos protocolos hormonales de superestimulación: protocolo 1 (Prot.1, FSH convencional de 400mg en dosis decrecientes por cuatro días) y protocolo 2 (Prot. 2, eCG, 2500UI en dosis única). Durante la realización de los protocolos se hizo la evaluación ovárica de los folículos pre ovulatorios (FPO) y de los cuerpos lúteos (CLs) mediante ecografía. Así mismo se evaluó la calidad y tasa de embriones recuperados. Los resultados mostraron que el número y diámetro de FPO y CLs no mostraron diferencias significativas entre los protocolos, de la misma forma el número de embriones colectados. Con eso se concluye que ambos protocolos de superovulación (FSH y eCG) son aplicables en bovinos pardo suizo altoandino. Palabras clave: vacas altoandinas, protocolo hormonal, FSH, eCG, embriones

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Induction of Superovulation in Domestic Ruminants

Cited by 6 publications

References 74 publications

Towards Improving the Outcomes of Multiple Ovulation and Embryo Transfer in Sheep, with Particular Focus on Donor Superovulation

Towards Improving the Outcomes of Multiple Ovulation and Embryo Transfer in Sheep, with Particular Focus on Donor Superovulation

Reuse of norgestomet implants in an eCG-based superovulation protocol administered to Nelore (Bos taurus indicus) cows

Respuesta ovárica y embrionaria de dos protocolos de superovulación en bovinos altoandinos Pardo Suizo

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