Induction of Prolonged Elevation of Interleukin 2 in the Culture Medium of Murine Splenocytes by Their Precultivation before Mitogenic Stimulations and Its Potentiation by Glucocorticoid Treatment and Restraint Stress Loading

Shibata, Hiroshi; Yamamoto, Ikuo

doi:10.1016/s0021-5198(19)40012-7

Japanese Journal of Pharmacology

1990

DOI: 10.1016/s0021-5198(19)40012-7

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Induction of Prolonged Elevation of Interleukin 2 in the Culture Medium of Murine Splenocytes by Their Precultivation before Mitogenic Stimulations and Its Potentiation by Glucocorticoid Treatment and Restraint Stress Loading

Hiroshi Shibata¹,

Ikuo Yamamoto²

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A Potential Anti-Tumor Herb Bred in a Tropical Fruit: Insight into the Chemical Components and Pharmacological Effects of Momordicae Semen

Luo

Cao

et al. 2019

Molecules

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Gac fruit (Momordica cochinchinensis Spreng) is a popular tropical fruit in southeast Asia. What is amazing is that its seeds (Momordicae Semen) and arils are traditional herbs with anti-tumor activity, and have protected human health for more than 1000 years. In recent years, its anti-tumor activity has received extensive attention and research. This manuscript summarized the chemical composition of saponins, fatty acids, volatile constituents, proteins, peptides, and other components from Momordicae Semen (MSE). The effect and mechanism of MSE and its extract on breast cancer, gastric cancer, lung cancer, esophagus cancer, melanomas, and human cervical epithelial carcinoma were discussed. In addition, its antioxidant, anti-inflammatory, and other pharmacological effects were also analyzed. We hope that this review will provide new ideas for the treatment of cancer and other diseases, and become a reference for the further research into complementary and alternative medicine.

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A Potential Anti-Tumor Herb Bred in a Tropical Fruit: Insight into the Chemical Components and Pharmacological Effects of Momordicae Semen

Luo

Cao

et al. 2019

Molecules

View full text Add to dashboard Cite

show abstract

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Induction of Prolonged Elevation of Interleukin 2 in the Culture Medium of Murine Splenocytes by Their Precultivation before Mitogenic Stimulations and Its Potentiation by Glucocorticoid Treatment and Restraint Stress Loading

Cited by 1 publication

References 41 publications

A Potential Anti-Tumor Herb Bred in a Tropical Fruit: Insight into the Chemical Components and Pharmacological Effects of Momordicae Semen

A Potential Anti-Tumor Herb Bred in a Tropical Fruit: Insight into the Chemical Components and Pharmacological Effects of Momordicae Semen

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