Induction of Labor Using One Dose versus Multiple Doses of Misoprostol: RCT

Abstract

Background: Situations arise in obstetrics where it becomes necessary to end a pregnancy in the interest of the mother or baby or both. There is a growing interest in the use of misoprostol, a prostaglandin E1 analogue for labour induction. Induction of labour is a common obstetric intervention and the use of misoprostol as an induction agent is important due to its low cost and stability at room temperature. These additional advantages make it a suitable agent, particularly in under-resourced settings and tropical countries. Aim of Study: This study was conducted to compare the rate of vaginal delivery within 24 hour among patients who undergo induction of labor between those who receive vaginal single dose of misoprostol with those receive up to 5 doses of this medication. Patients and Methods: The study was a randomized controlled open labeled clinical trial, study setting was Ob