Induction of Emesis by the Sodium Channel Activator Veratrine in the Lesser Spotted Dogfish, <i>Scyliorhinus Canicula</i> (Chondrichthyes: Elasmobranchii)

Andrews, Paul; Sims, David; Young, J. Z.

doi:10.1017/s0025315400044489

Cited by 8 publications

(7 citation statements)

References 20 publications

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“…Veratrine is an activator of sodium channels in saliva, and induces vomiting (Andrews et al, 1998). The antifeedant activity of veratrine against weevils as identified by this study (antifeedant rate 59.43% at 2 g•L -1 ) and against Helicoverpa armigera as reported by Tian et al (2018) may be related to its emesis-inducing property.…”

Section: Resultssupporting

confidence: 68%

Evaluation of ten botanical insecticides against the sweet potato Weevil, Cylas formicarius (Fabricius, 1798) (Coleoptera: Brentidae)

Ren¹,

Zheng²,

Chen³

et al. 2020

Afr. J. Agric. Res.

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The sweet potato weevil, Cylas formicarius (Fabricius) (Coleoptera: Brentidae), is a destructive insect pest that damages sweet potatoes both in the field and during storage. To identify new environmentally friendly insecticides to control this insect pest, three assays (olfactory test, anti-feeding assay, and toxicity assay) were conducted to evaluate the efficacy and mode of action of 10 botanical insecticides against C. formicarius adults in 2015 and 2016. Of these 10 botanical insecticides, tea saponin, pyrethrins, and veratrine showed significant repellency in olfactory tests. Eight botanical insecticides showed anti-feeding effects in the feeding choice test. Five botanical insecticides had high toxicity. Among them, the lethal concentrations of rotenone were lowest followed by pyrethrins. The lethal time values of rotenone were shortest followed by nicotine. In conclusion, rotenone, pyrethrins, nicotine, and toosendanin have the potential to control C. formicarius adults. Of these, pyrethrins and toosendanin are more environmentally friendly than rotenone and nicotine and were identified as better insecticides to control C. formicarius.

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Section: Resultssupporting

confidence: 68%

Evaluation of ten botanical insecticides against the sweet potato Weevil, Cylas formicarius (Fabricius, 1798) (Coleoptera: Brentidae)

Ren¹,

Zheng²,

Chen³

et al. 2020

Afr. J. Agric. Res.

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“…Some species filter‐feed at the surface where individuals can be tracked visually and where prey densities can be sampled directly using plankton nets (Sims et al ., 1997). Furthermore, sharks have a large cardiac stomach, which coupled with their slow rates of digestion (Sims et al ., 1996) and propensity to vomit readily (Andrews et al ., 1998), means that routine recovery of stomach contents is feasible. A slow digestion rate is particularly useful for examining recent feeding history because predatory species that consume large prey whole may contain items at various stages of digestion, the chronology of which may then be matched to tracked movements.…”

Section: Sharks As Models: Practical Considerationsmentioning

confidence: 99%

Tractable models for testing theories about natural strategies: foraging behaviour and habitat selection of free‐ranging sharks

Sims

2003

Journal of Fish Biology

112

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Marine and terrestrial environments differ fundamentally in space-time scales of both physical and ecological processes. These differences will have an impact on the animals inhabiting each domain, particularly with respect to their spatial ecology. The behavioural strategies that underpin observed distributions of marine species are therefore important to consider. Comparatively little is known, however, about how wild fishes actually respond to gradients in food supply and temperature, and to potential mates. This paper describes how behavioural theory is being used to elucidate the strategies and tactics of free-ranging sharks in three specific areas of study, namely, foraging on zooplankton, behavioural energetics and sexual segregation. The studies discussed are novel because shark movements were tracked in the wild using electronic tags in relation to simultaneous measurements of prey densities and thermal resources. The results show that filter-feeding (basking shark, Cetorhinus maximus) and predatory (dogfish, Scyliorhinus canicula) sharks have relatively complex behaviour patterns integrally linked to maximizing surplus power, often through making short and longer term 'trade-off' decisions between optimal foraging and thermal habitats. Interestingly, female S. canicula exhibit alternative behavioural strategies compared to males, a difference resulting in spatial segregation by habitat. Sexual segregation in this species occurs primarily as a consequence of male avoidance by females. Studies on free-ranging sharks provide a useful model system for examining how a predator's strategy is shaped by its environment. More theory-based studies of the behavioural processes of sharks are required however, before critical comparisons with other vertebrate predators are possible. Suggestions for further research to address this knowledge gap are given.

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“…The gene sodium channel, non-voltage-gated 1 alpha subunit (SCNN1A) is responsible for controlling fluid and electrolyte transport across epithelia in many organs. The close relationship between sodium channel and vomiting has been partially approved in [20] by experiments on fishes. Dexamethasone is an anti-inflammatory drug.…”

Section: Co-modules Of Drugs and Targets By The Mpgraphmentioning

confidence: 99%

MPGraph: multi‐view penalised graph clustering for predicting drug–target interactions

Liu

2014

IET Systems Biology

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Identifying drug-target interactions has been a key step for drug repositioning, drug discovery and drug design. Since it is expensive to determine the interactions experimentally, computational methods are needed for predicting interactions. In this work, the authors first propose a single-view penalised graph (SPGraph) clustering approach to integrate drug structure and protein sequence data in a structural view. The SPGraph model does clustering on drugs and targets simultaneously such that the known drug-target interactions are best preserved in the clustering results. They then apply the SPGraph to a chemical view with drug response data and gene expression data in NCI-60 cell lines. They further generalise the SPGraph to a multi-view penalised graph (MPGraph) version, which can integrate the structural view and chemical view of the data. In the authors' experiments, they compare their approach with some comparison partners, and the results show that the SPGraph could improve the prediction accuracy in a small scale, and the MPGraph can achieve around 10% improvements for the prediction accuracy. They finally give some new targets for 22 Food and Drug Administration approved drugs for drug repositioning, and some can be supported by other references.

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Induction of Emesis by the Sodium Channel Activator Veratrine in the Lesser Spotted Dogfish, Scyliorhinus Canicula (Chondrichthyes: Elasmobranchii)

Cited by 8 publications

References 20 publications

Evaluation of ten botanical insecticides against the sweet potato Weevil, Cylas formicarius (Fabricius, 1798) (Coleoptera: Brentidae)

Evaluation of ten botanical insecticides against the sweet potato Weevil, Cylas formicarius (Fabricius, 1798) (Coleoptera: Brentidae)

Tractable models for testing theories about natural strategies: foraging behaviour and habitat selection of free‐ranging sharks

MPGraph: multi‐view penalised graph clustering for predicting drug–target interactions

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