Inductance Plethysmography: An Alternative Signal to Servocontrol the Airway Pressure during Proportional Assist Ventilation in Small Animals

Influence of neurally adjusted ventilatory assist and positive end-expiratory pressure on breathing pattern in rabbits with acute lung injury*

“…Schulze et al (47,48) showed that with proportional assist ventilation, overcompensation of elastic loads in salinelavaged rabbits caused passive lung inflation, increased Pes, and produced fluctuations in blood pressure, whereas overcompensation of resistive load with proportional assist ventilation produced resonant amplitude oscillations. In our study, increases to supra-high levels of NAVA gain resulted in a periodic breathing pattern in which phasic breathing pattern was interrupted by periods of apnea; however, there was no indication for passive lung inflation, resonating frequency oscillations, or "runaway.…”