Inducing Labour by Intra-amniotic Injection

Abstract

CORRESPONDENCE MEDICsL JOH 1129 convincing, and will continue to maintain this opinion until Dr. Porter publishes the evidence on which, I presume, his contrary opinion is based. (3) In the case of lung carcinoma, more toxic doses of mustine give no greater degree or duration of palrliation than the generally accepted " safe " dose (0.4 mg. per kilo). This opinion results from ten years' experience of such therapy. Apparently Dr. Porter has no personal contribution to make in this matter nor reports to oppose my findings. I would like to finish this letter with a plea. Palliative chemotherapy of cancer is in its infancy, and the benefit from most agents is short-lived. My purpose in starting this correspondence was referred to in my first letter when I wrote of the danger of piling misery upon misery in the late cancer case. I meant particularly the danger of gross marrow depression from injudicious chemotherapy, which may require repeated transfusions often daily for a period of two to three weeks in some cases. To have had no patients die from toxicity is, in my opinion, either a manifestation of good fortuine, short experience, or misinterpretation of necropsy findings.-I