Induced Pluripotent Stem Cells and Organoids in Advancing Neuropathology Research and Therapies
Douglas Pazzin,
Thales Previato,
João Budelon Gonçalves
et al.
Abstract:This review delves into the groundbreaking impact of induced pluripotent stem cells (iPSCs) and three-dimensional organoid models in propelling forward neuropathology research. With a focus on neurodegenerative diseases, neuromotor disorders, and related conditions, iPSCs provide a platform for personalized disease modeling, holding significant potential for regenerative therapy and drug discovery. The adaptability of iPSCs, along with associated methodologies, enables the generation of various types of neural… Show more
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