2021
DOI: 10.7759/cureus.20014
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Induced Native Phage Therapy for the Treatment of Lyme Disease and Relapsing Fever: A Retrospective Review of First 14 Months in One Clinic

Abstract: The overall failure rate of standard therapeutic options for late/chronic/persistent borreliosis emphasizes the need for novel therapeutic strategies. In this report, we are presenting a novel therapeutic option based on a new technology, Induced Native Phage Therapy (INPT; PhagenCorp, LLC, Sarasota, FL), and its ability to facilitate the elimination of infection more rapidly, efficiently, and with less harm to the patient than conventional treatments. Borrelia species in the environmen… Show more

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Cited by 4 publications
(4 citation statements)
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“…Other factors that are literally coming to light and the electro-magnetic frequnecies at distinct wavelengths that can, like the microwaves in everyone's kitchen, be tuned to particular molecular entities from water molecules to virions, bacteria, and brain cells. Certain metals and carbon-based composites(Jernigan & Joseph, 2005;Jernigan et al 2021;Yanowitz, 2022) have been implicated along with the strange abnormal clots discussed above in this paper.…”
mentioning
confidence: 82%
“…Other factors that are literally coming to light and the electro-magnetic frequnecies at distinct wavelengths that can, like the microwaves in everyone's kitchen, be tuned to particular molecular entities from water molecules to virions, bacteria, and brain cells. Certain metals and carbon-based composites(Jernigan & Joseph, 2005;Jernigan et al 2021;Yanowitz, 2022) have been implicated along with the strange abnormal clots discussed above in this paper.…”
mentioning
confidence: 82%
“…However, these discoveries need further refinement to identify specific chemical compositions and activity of these compounds as well as safety and pharmacokinetic studies in several animal models before a more conclusive determination for their efficacy can be made. Other novel treatments recommended for targeting Bb include inhibiting colonization by blocking binding to glycosaminoglycan (GAG) proteins ( 189 ), delivering toxic molecules and binding essential enzymes ( 190 ) and bacteriophage therapy ( 191 ). These innovative ideas are still in early phases of development and testing.…”
Section: Next Generation Treatments and Biomarkersmentioning
confidence: 99%
“…The BES findings were subsequently verified by the recently developed and highly accurate laboratory test, the Phelix Borrelia-Phage test. This test is reported as having a 96% sensitivity and 100% specificity in acute, chronic, or antibiotic-resistant infections [ 14 ].…”
Section: Introductionmentioning
confidence: 99%
“…Upon retesting using the Phelix Borrelia-Phage test, only the targeted strain was tested as eliminated, while the untreated strain persisted. When this latter strain was targeted using the BES to strategically induce other polyvalent phages to eliminate the remaining strain of Borrelia , repeat Phelix Borrelia-Phage testing resulted in it being apparently eliminated [ 14 ]. No adverse effects of the treatment were reported, nor was there a typical Jarisch-Herxheimer reaction worsening of the patient's symptoms due to the speed of bacteriophage killing of the targeted infection and the absence of bacterial toxins in Borrelia spirochetes [ 15 ].…”
Section: Introductionmentioning
confidence: 99%