Induced membrane technique: a critical literature analysis and proposal for a failure classification scheme

Laurent, Michel; Durand, Marjorie; Collombet, Jean-Marc; Rousiers, Arnaud de; l’Escalopier, Nicolas de; Masquelet, Alain-Charles

doi:10.1007/s00068-020-01540-9

Cited by 19 publications

(28 citation statements)

References 43 publications

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“…Since then, we have repeatedly published on IMT use in the various settings of our military practice. Like civilian authors, we have found that this technique achieves satisfying outcomes in bone union and complication rates [3,12,[15][16][17][18][19][20][21][22]. We have also demonstrated that IMT is suited for bone defects of ballistic origin and can be applied in the austere environment of forward surgical units [12,17,22].…”

Section: Introductionmentioning

confidence: 74%

Masquelet technique in military practice: specificities and future directions for combat-related bone defect reconstruction

Mathieu

Mourtialon

Durand³

et al. 2022

Military Med Res

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Because of its simplicity, reliability, and replicability, the Masquelet induced membrane technique (IMT) has become one of the preferred methods for critical bone defect reconstruction in extremities. Although it is now used worldwide, few studies have been published about IMT in military practice. Bone reconstruction is particularly challenging in this context of care due to extensive soft-tissue injury, early wound infection, and even delayed management in austere conditions. Based on our clinical expertise, recent research, and a literature analysis, this narrative review provides an overview of the IMT application to combat-related bone defects. It presents technical specificities and future developments aiming to optimize IMT outcomes, including for the management of massive multi-tissue defects or bone reconstruction performed in the field with limited resources.

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Section: Introductionmentioning

confidence: 74%

Masquelet technique in military practice: specificities and future directions for combat-related bone defect reconstruction

Mathieu

Mourtialon

Durand³

et al. 2022

Military Med Res

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“…Although the practice of cement loading with antibiotics has been controversial, [ 23 ] in the herein study the cement spacer was loaded with gentamycininallpatients and ina recentmeta-analysis it was found that it decreased the need for revision. [ 24 ] We do not add methylene blue to the cement during the first stage as we have found no issues with cement identification during the second stage.…”

Section: Discussionmentioning

confidence: 99%

Induced membrane technique for acute bone loss and nonunion management of the tibia

Chloros

Kanakaris

Harwood

et al. 2022

OTA International: The Open Access Journal of Orthopaedic Trauma

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Objectives: To report our experience and clinical results of using the Masquelet technique for the treatment of tibial nonunions and acute traumatic tibial bone defects.Design: Retrospective study of prospectively collected data (Level IV).Setting: Level I trauma center in the UK.Patients/Participants: Consecutive patients with tibial nonunions and open fractures associated with bone loss.Intervention: Two-stage Masquelet Procedure for the tibia.Main Outcome Measurements: Clinical and imaging assessment at 6 weeks, 3,6,9,12 months, or until pain-free mobilization and union.Results: There were 17 eligible patients, with a mean size of bone defect of 6 cm (range, 4-8 cm) and an 88.2% union rate at a mean of 8 months (range 5-18 months). Mean range of motion was 95 degrees of knee flexion (range 80°-130°). All patients but 2 returned to their previous occupation. Conclusions:The Masquelet technique is simple, effective, and has a high rate of success for the management of a variety of situations including acute bone loss or infected nonunions and is associated with a low incidence of complications.

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“…Thus, they recommended further studies on the effect of BMP within IMT. Lastly, Mathieu et al 42 reviewed the 2 meta-analyses 8,12 and concluded that the addition of recombinant growth factor is still controversial because no clinical comparative study has proven their values.…”

Section: Discussionmentioning

confidence: 99%

Effect of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) with Hydroxyapatite Carrier in Induced Membrane Technique: A Retrospective Propensity Score-Matched Study

Son

Lim²,

Sakong³

et al. 2022

Journal of Orthopaedic Trauma

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Induced membrane technique: a critical literature analysis and proposal for a failure classification scheme

Cited by 19 publications

References 43 publications

Masquelet technique in military practice: specificities and future directions for combat-related bone defect reconstruction

Masquelet technique in military practice: specificities and future directions for combat-related bone defect reconstruction

Induced membrane technique for acute bone loss and nonunion management of the tibia

Effect of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) with Hydroxyapatite Carrier in Induced Membrane Technique: A Retrospective Propensity Score-Matched Study

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