Indolyl‐4H‐Chromene Derivatives as Antibacterial Agents: Synthesis, in Vitro and in Silico Studies
Parthiban Anaikutti,
Priyanka Adhikari,
Sambath Baskaran
et al.
Abstract:In this study, indolyl‐4H‐chromene derivatives are designed and synthesised using an eco‐friendly multicomponent one‐pot synthesis using benzaldehydes, nitroketene N, S‐acetals, and indoles combine with InCl3, a Lewis acid catalyst, and ethanol, an environmentally acceptable solvent. Due to antibiotic resistance, assessed these Indolyl‐4H‐chromene derivatives for their in vitro antibacterial activity against Gram‐positive and Gram‐negative bacteria, including Streptococcus pyogenes, Staphylococcus aureus, Clos… Show more
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