Indocyanine green (ICG) fluorescence detection from colon tissue using flexible bundle-fiber optics

Advancing indocyanine green fluorescence flap perfusion assessment via near infrared signal quantification

“…This highlights the importance of dosing, which results in greater fluorescence intensity with ICG concentration up to 1.6 mg/kg. 32 For this system, our findings support the working guidance of the International Society for Fluorescence Guided Surgery (ISFGS) which recommends a weight independent dose of 3 ml for mastectomy flap perfusion assessment 15 (or a dose of 0.11 mg/kg for a reference male 33 of 70 kg). Although IFSGS admit that further research on dosing is needed and is yet to specify a dose for FF reconstruction, it is likely that a similarly reduced dose would be suitable for this system (but is likely too low for the laparoscopic one).…”