Indocyanine green augmented transpupillary thermotherapy in the management of choroidal metastasis from breast carcinoma

Abstract

Indocyanine green augmented transpupillary thermotherapy is a viable alternative for management of solitary choroidal metastasis from breast carcinoma.

Subthreshold Transpupillary Thermotherapy for Early Resolution of Foveal Subretinal Fluid in Choroidal Metastasis

“…5,6 The treatment modalities are versatile, but the effects are not impressive. The metastatic choroidal tumor presents as a yellowish, elevated, diffuse lesion with irregular borders.…”

“…The metastatic choroidal tumor presents as a yellowish, elevated, diffuse lesion with irregular borders. 1,5,6 Hyperthermia is the elevation of body temperature above the normal of 37°C. Treatment is usually recommended if the tumor appears active and threatens vision despite concomitant systemic chemotherapy.…”

The effect of indocyanine green pretreatment on the parameters of transscleral diode laser thermotherapy‐induced threshold coagulation of the ciliary body

“…Puri et al reported the use of ICG-augmented transpupillary thermotherapy in the management of choroidal metastasis from breast carcinoma [20]. The investigators concluded that the combination of ICG and TTT was promising for the management of small, potentially sightthreatening choroidal metastasis [20].…”

“…The investigators concluded that the combination of ICG and TTT was promising for the management of small, potentially sightthreatening choroidal metastasis [20]. Costa et al used ICG as a photosensitizer in an experimental study on photodynamic therapy [25], and in the treatment of occult subfoveal choroidal neovascularization caused by agerelated macular degeneration [21].…”

“…After intravenous injection, the main peak of the absorption spectrum of ICG is observed at 805 nm, [17] which just coincides with the emission wavelength of the diode laser (810 nm). ICG has been combined with diode laser application to induce vascular closure in the treatment of AIDS-associated cutaneous Kaposi's sarcoma [18], colon cancer, [19] choroidal metastasis from breast carcinoma [20], and occult subfoveal choroidal neovascularization caused by age-related macular degeneration [21].…”