Indocyanine green applications in hepato-biliary surgery

Cassese, Gianluca; Troisi, Roberto

doi:10.23736/s2724-5691.21.08809-2

Cited by 9 publications

(3 citation statements)

References 13 publications

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“…Для уменьшения частоты послеоперационных осложнений, наряду с рутинным применением ИОУЗИ, широко внедряют флюоресцентную ИЦЗ-диагностику как для контрастирования опухоли, сосудов и протоков, так и для определения границ резекции [18][19][20]. Поскольку пациентам с выраженным ЦП необходимо выполнять экономные анатомические резекции, внедряют методы сегментации.…”

Section: Discussionunclassified

Minimally invasive surgery for hepatocellular carcinoma

et al. 2022

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Aim. To evaluate outcomes of laparoscopic liver resections in patients with hepatocellular carcinoma (HCC).Materials and methods. 40 endovideosurgical liver resections were performed in patients with HCC in the period of 2011–2021. Concomitant cirrhosis was detected in 36 cases (90%).Results. The average duration of surgery was 158.1 ± 78.6 min. The duration of anatomical lobar resections appeared to be the longest – 230 min. The average volume of intraoperative blood loss was 259.5 ± 260.5 ml, which almost excluded blood transfusions. The duration of hospitalization comprised 11.2 ± 2.3 days. One-year survival was achieved in 95% of cases, two-year – in 81%, three-year – in 64%.Conclusion. Laparoscopic liver resections in hepatocellular carcinoma prove to be safe and provide satisfactory surgical and oncological outcomes.

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Section: Discussionunclassified

Minimally invasive surgery for hepatocellular carcinoma

et al. 2022

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“…In our experience, LLR for multinodular HCC is safe and feasible. However, some precautions are essential to reaching adequate oncologic outcomes, such as a high expertise in ultrasonography-guided parenchymal dissection with intraoperative ICG-guided fluorescence that can further help detect HCC nodules and guide difficult parenchymal dissection, while 3D-high definition scopes could represent an additional supportive visual tool [ 91 , 92 ]. Further technological research is supposed to help surgeons in this scenario, such as the application of 3-D preoperative modeling and virtual realities, which could also be beneficial in this context [ 93 ].…”

Section: Minimally Invasive Approach For Multiple Hepatocellular Carc...mentioning

confidence: 99%

Selecting the Best Approach for the Treatment of Multiple Non-Metastatic Hepatocellular Carcinoma

Cassese

Han

Cho

et al. 2022

Cancers

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According to the Barcelona Clinic Liver Cancer (BCLC) staging system, the optimal strategy for patients with multiple HCC within the Milan Criteria is liver transplantation (LT). However, LT cannot be offered to all the patients due to organ shortages and long waiting lists, as well as because of the advanced disease carrying a high risk of poor outcomes. For early stages, liver resection (LR) or thermal ablation (TA) can be proposed, while trans-arterial chemoembolization (TACE) still remains the treatment of choice for intermediate stages (BCLC-B). Asian guidelines and the National Comprehensive Cancer Network suggest LR for resectable multinodular HCCs, even beyond Milan criteria. In this scenario, a growing body of evidence shows better outcomes after surgical resection when compared with TACE. Trans-arterial radioembolization (TARE) and stereotaxic body radiation therapy (SBRT) can also play an important role in this setting. Furthermore, the role of minimally invasive liver surgery (MILS) specifically for patients with multiple HCC is still not clear. This review aims to summarize current knowledge about the best therapeutical strategy for multiple HCC while focusing on the role of minimally invasive surgery and on the most attractive future perspectives.

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“…Near-infrared fluorescence (NIRF) imaging using indocyanine green (ICG) is a new real-time navigation tool widely used in laparoscopic and open hepatobiliary surgery [ 79 ]. In 2018, Seo et al first published their experience with ICG-guided fluorescence, during four cases of open radical cholecystectomy, by injecting the dye inside the cystic artery through a conventional open approach.…”

Section: Clinical Management According To the Depth Of Invasionmentioning

confidence: 99%

Preoperative Assessment and Perioperative Management of Resectable Gallbladder Cancer in the Era of Precision Medicine and Novel Technologies: State of the Art and Future Perspectives

et al. 2022

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Gallbladder carcinoma (GBC) is a rare malignancy, with an estimated 5-year survival rate of less than 5% in the case of advanced disease. Surgery is the only radical treatment for early stages, but its application and effectiveness depend on the depth of tumoral invasion. The extent of resection is usually determined according to the T-stage. Therefore, an early and correct preoperative assessment is important for the prognosis, as well as for the selection of the most appropriate surgical procedure, to avoid unnecessary morbid surgeries and to reach the best outcomes. Several modalities can be used to investigate the depth of invasion, from ultrasounds to CT scans and MRI, but an ideal method still does not exist. Thus, different protocols are proposed according to different recommendations and institutions. In this scenario, the indications for laparoscopic and robotic surgery are still debated, as well as the role of new technologies such as next-generation sequencing and liquid biopsies. The aim of this article is to summarize the state of the art current modalities and future perspectives for assessing the depth of invasion in GBC and to clarify their role in perioperative management accordingly.

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Indocyanine green applications in hepato-biliary surgery

Cited by 9 publications

References 13 publications

Minimally invasive surgery for hepatocellular carcinoma

Minimally invasive surgery for hepatocellular carcinoma

Selecting the Best Approach for the Treatment of Multiple Non-Metastatic Hepatocellular Carcinoma

Preoperative Assessment and Perioperative Management of Resectable Gallbladder Cancer in the Era of Precision Medicine and Novel Technologies: State of the Art and Future Perspectives

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