Indocyanine green and iohexol loaded hydroxyapatite in poly(L‐lactide‐co‐caprolactone)‐based composite for bimodal near‐infrared fluorescence‐ and X‐ray‐based imaging
Żaneta Górecka,
Joanna Idaszek,
Marcin Heljak
et al.
Abstract:This study aimed to develop material for multimodal imaging by means of X‐ray and near‐infrared containing FDA‐ and EMA‐approved iohexol and indocyanine green (ICG). The mentioned contrast agents (CAs) are hydrophilic and amphiphilic, respectively, which creates difficulties in fabrication of functional polymeric composites for fiducial markers (FMs) with usage thereof. Therefore, this study exploited for the first time the possibility of enhancing the radiopacity and introduction of the NIR fluorescence of FM… Show more
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