2015
DOI: 10.7146/kok.v43i120.22967
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Indledning - (U)sunde kroppe

Abstract: Dette nummer af K&K handler om (u)sunde kroppe. Krop og sundhed er i det senmoderne blevet temaer, der optager stadig større dele af befolkningen, og som i saerlig grad antager politisk betydning. Blogs og V-logs om traening og ernaering, ugentlige detoxkure og selvrealisering gennem motion er blevet hverdag for mange. Fra vuggestuernes udvidede sukkerpolitik til virksomhedernes krav om og monitorering af medarbejdernes helbredstilstand, er vi blevet vant til at blive konfronteret med kravet om konstant optime… Show more

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“…Due to the very similar binding mode of 6b, 7a and AMPA, we find that the most likely explanation for this difference in binding affinity is the difference in pK a values for the 4-hydroxy-1,2,3-triazole moiety (6b: 6.42 and 7a: 6.11) 41 compared to that of AMPA (4.8). 49 Furthermore, the structural changes of Met729 in the GluA2-ABD accompanied by the difference in binding site water network might also contribute to the observed differences in binding affinities.…”
Section: Structurementioning
confidence: 99%
“…Due to the very similar binding mode of 6b, 7a and AMPA, we find that the most likely explanation for this difference in binding affinity is the difference in pK a values for the 4-hydroxy-1,2,3-triazole moiety (6b: 6.42 and 7a: 6.11) 41 compared to that of AMPA (4.8). 49 Furthermore, the structural changes of Met729 in the GluA2-ABD accompanied by the difference in binding site water network might also contribute to the observed differences in binding affinities.…”
Section: Structurementioning
confidence: 99%