Individualized managing strategies of aggressive angiomyxoma of female genital tract and pelvis

Bai, Huimin; Yang, Juan-jun; Huang, Hanyuan; Cao, Dongyan; Chen, Jianwei; Yang, Ning; Lang, Jing He; Shen, Keng

doi:10.1016/j.ejso.2013.06.013

Cited by 32 publications

(51 citation statements)

References 21 publications

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“…1,2,25 treatment of perineal sarcomas is particularly challenging because it is a balance between the "wide surgery" required for sarcomas, 26 which aims to be R0, and the preservation of functional organs. [1][2][3][4][22][23][24] for desmoid tumors, particularly in postpartum female patients, a nonsurgical option may be the first step because spontaneous regressions frequently occur. Compared with retroperitoneal sarcomas, where the resection of some adjacent organs may be performed without definitive sequelae, 26 surgery for sarcoma of the perineum may lead to mutilations.…”

Section: Discussionmentioning

confidence: 99%

Algorithm for the Surgical Management of Mesenchymal Tumors of the Perineum in Adults

Sourrouille

Vilcot

Honoré

et al. 2015

Diseases of the Colon &Amp; Rectum

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Section: Discussionmentioning

confidence: 99%

Algorithm for the Surgical Management of Mesenchymal Tumors of the Perineum in Adults

Sourrouille

Vilcot

Honoré

et al. 2015

Diseases of the Colon &Amp; Rectum

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“…The presence of multiple feeding vessels also limits the use of embolization as a treatment modality [11]. Individualization of the treatment options and multimodal treatment seem to be the most appropriate [16,17].…”

Section: Discussionmentioning

confidence: 99%

Aggressive Angiomyxoma of the Cervix: A Unique Entity

S¹

2014

Glob J Medical Clin Case Rep

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Introduction: Aggressive angiomyxoma is a mesenchymal tumour which presents rarely; usually in women in reproductive age group, as a mass in the pelvic tissue. Only exceptionally, has it been seen to originate from the uterus and cervix. Methods:We present a case of a 23-year-old woman who complained about abdominal pain and excessive vaginal bleeding three days after a spontaneous abortion. Examination revealed a large polyp arising from the cervix. Histopathologic examination of the polypectomy specimen revealed an aggressive angiomyxoma of the cervix. Immunohistochemistry was performed and the tumour was immunopositive for vimentin, desmin and smooth muscle actin. Management options are discussed, in light of need of fertility conservation.Result: Aggressive angiomyxoma can originate from the mesenchymal tissue of the cervix.Conclusions: Treatment may be individualized with surgery and hormonal treatment. Long term follow up is recommended.

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“…Although usually a benign lesion, aggressive angiomyxoma is difficult to excise because of the extent of the lesion and the lack of circumscription, and has a tendency to recur locally. 15 Due to the potential hormonal sensitivity of these lesions, GnRh agonists have been utilized preoperatively to shrink lesions, and as an adjuvant therapy for incompletely excised or recurrent cases. 15 The differential diagnosis includes angiomyofibroblastoma and other myxoid soft tissue neoplasms; soft tissue lesions that may be confused histopathologically.…”

Section: Aggressive Angiomyxomamentioning

confidence: 99%

“…15 Due to the potential hormonal sensitivity of these lesions, GnRh agonists have been utilized preoperatively to shrink lesions, and as an adjuvant therapy for incompletely excised or recurrent cases. 15 The differential diagnosis includes angiomyofibroblastoma and other myxoid soft tissue neoplasms; soft tissue lesions that may be confused histopathologically. Distinction is important, as angiomyofibroblastoma is well circumscribed, and unlikely to recur after surgical excision.…”

Section: Aggressive Angiomyxomamentioning

confidence: 99%