2020
DOI: 10.1016/j.wneu.2020.04.240
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Individualized Anatomy-Based Targeting for VIM-cZI DBS in Essential Tremor

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Cited by 12 publications
(13 citation statements)
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“…We assume a homogeneous isotropic system throughout our testing, where the elements of are given according to the population and electrode positions where we have omitted the constant κ e for simplicity. Generating relevant configurations also requires an appropriate choice of L , which we choose according to a sensible estimate ( L = 3) of how many contacts can be implanted in the VIM with present generation DBS leads [ 38 40 ]. To generate a particular electrode-population configuration, we first approximate the shape of the VIM to be a sphere of unit radius.…”
Section: Resultsmentioning
confidence: 99%
“…We assume a homogeneous isotropic system throughout our testing, where the elements of are given according to the population and electrode positions where we have omitted the constant κ e for simplicity. Generating relevant configurations also requires an appropriate choice of L , which we choose according to a sensible estimate ( L = 3) of how many contacts can be implanted in the VIM with present generation DBS leads [ 38 40 ]. To generate a particular electrode-population configuration, we first approximate the shape of the VIM to be a sphere of unit radius.…”
Section: Resultsmentioning
confidence: 99%
“…The PSA (cZi) target was located 1 mm medial to the intersection of the blue and white lines. Regarding the Vim, the stereotactic coordinates were 12–14 mm lateral, 4–6 mm posterior, and 0–1 mm inferior to the MCP [ 20 , 23 , 26 ]. Both targets were adjusted and verified with the DTI and FGATIR images.…”
Section: Methodsmentioning
confidence: 99%
“…The PSA is anatomically situated ventromedial to the Vim, conforming to the direction (from anterior superior lateral to posterior inferior medial) of the accustomed trajectory. Several institutions have attempted to perform Vim–PSA electrode implantation surgery by aligning the Vim and PSA in a single electrode [ 17 , 18 , 19 , 20 ]. These studies suggested that the efficacy of double-target stimulation is similar to that of single-target stimulation (Vim or PSA) in alleviating tremors.…”
Section: Introductionmentioning
confidence: 99%
“…The existing brain atlas individualization techniques are single-subject based or multi-subject based. Single-subject-based individualization relies on high-quality diffusion MRI data to reconstruct fiber projections between ROI and cerebral cortex 24,57,63,64 , or robust parcellation algorithms to assign voxels into corresponding clusters 52,60,65 . And they lack canonical cluster labeling criteria and population commonality.…”
Section: Introductionmentioning
confidence: 99%