Individualised renal artery denervation improves blood pressure control in Kazakhstani patients with resistant hypertension

Арипов, М.А.; Mussayev, Abdurashid; Alimbayev, Serik; Гончаров, А. В.; Жусупова, Г К; Pya, Yuriy

doi:10.5603/kp.a2016.0096

Cited by 4 publications

(1 citation statement)

References 25 publications

(31 reference statements)

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“…Also, similar studies have shown possible alterations of insulin sensitivity mediated by RDN. More specifically, Aripov et al [ 40 ], in a study assessing RDN’s effect in 63 patients with resistant hypertension, noted a significant reduction of the homeostasis model assessment-insulin resistance (HOMA-IR) index, which was significantly reduced by a mean of 0.5 at 12 months.…”

Section: Renal Denervation and Glycemic Control: Preclinical And Clin...mentioning

confidence: 99%

Unravelling the effect of renal denervation on glucose homeostasis: more questions than answers?

Koutra,

Dimitriadis,

Pyrpyris

et al. 2023

Acta Diabetol

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Renal Denervation (RDN) is an interventional, endovascular procedure used for the management of hypertension. The procedure itself aims to ablate the renal sympathetic nerves and to interrupt the renal sympathetic nervous system overactivation, thus decreasing blood pressure (BP) levels and total sympathetic drive in the body. Recent favorable evidence for RDN resulted in the procedure being included in the recent European Guidelines for the management of Hypertension, while RDN is considered the third pillar, along with pharmacotherapy, for managing hypertension. Sympathetic overactivation, however, is associated with numerous other pathologies, including diabetes, metabolic syndrome and glycemic control, which are linked to adverse cardiovascular health and outcomes. Therefore, RDN, via ameliorating sympathetic response, could be also proven beneficial for maintaining an euglycemic status in patients with cardiovascular disease, alongside its BP-lowering effects. Several studies have aimed, over the years, to provide evidence regarding the pathophysiological effects of RDN in glucose homeostasis as well as investigate the potential clinical benefits of the procedure in glucose and insulin homeostasis. The purpose of this review is, thus, to analyze the pathophysiological links between the autonomous nervous system and glycemic control, as well as provide an overview of the available preclinical and clinical data regarding the effect of RDN in glycemic control.

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Section: Renal Denervation and Glycemic Control: Preclinical And Clin...mentioning

confidence: 99%

Unravelling the effect of renal denervation on glucose homeostasis: more questions than answers?

Koutra,

Dimitriadis,

Pyrpyris

et al. 2023

Acta Diabetol

View full text Add to dashboard Cite

show abstract

Effects of catheter-based renal denervation on glycemic control and lipid levels: a systematic review and meta-analysis

2021

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Device-based therapies for arterial hypertension

et al. 2020

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Individualised renal artery denervation improves blood pressure control in Kazakhstani patients with resistant hypertension

Abstract: In this population RAD resulted in statistically and clinically significant blood pressure reduction at 12 months with minimal adverse events.

Cited by 4 publications

References 25 publications

Unravelling the effect of renal denervation on glucose homeostasis: more questions than answers?

Unravelling the effect of renal denervation on glucose homeostasis: more questions than answers?

Effects of catheter-based renal denervation on glycemic control and lipid levels: a systematic review and meta-analysis

Device-based therapies for arterial hypertension

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